Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study
To investigate the risk of atrial fibrillation or atrial flutter in patients with periodontitis (PD) in comparison with individuals without PD. We used the 1999-2010 Taiwanese National Health Insurance Research Database to identify cases of PD in the year 2000 matching (1:1) with persons without PD...
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| description | To investigate the risk of atrial fibrillation or atrial flutter in patients with periodontitis (PD) in comparison with individuals without PD.
We used the 1999-2010 Taiwanese National Health Insurance Research Database to identify cases of PD in the year 2000 matching (1:1) with persons without PD during 1999-2000 according to sex and individual age as the control group. Using Cox proportional regression analysis adjusting for potential confounders, including age, sex, and comorbidities at baseline, and average annual number of ambulatory visits and dental scaling frequency during the follow-up period, we estimated hazard ratios (HRs) with 95% confidence intervals (CIs) to examine the risk of atrial fibrillation or flutter in PD patients in comparison with the control group. Subgroup analyses according to age, gender, or comorbidities were conducted to study the robustness of the association and investigate possible interaction effects.
We enrolled 393,745 patients with PD and 393,745 non-PD individuals. The incidence rates of atrial fibrillation or flutter were 200 per 105 years among the PD group and 181 per 105 years in the non-PD group (incidence rate ratio, 1.10; 95% CI, 1.06-1.14). After adjusting for potential confounders, we found an increased risk of atrial fibrillation or flutter in the PD group compared with the non-PD group (HR, 1.31; 95% CI, 1.25-1.36). The greater risk of atrial fibrillation or flutter in the PD group remained significant across all disease subgroups except hyperthyroidism and sleep apnea.
The present study results indicate an increased risk of atrial fibrillation or flutter in patients with PD. Lack of individual information about alcohol consumption, obesity, and tobacco use was a major limitation. |
| doi_str_mv | 10.1371/journal.pone.0165601 |
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We used the 1999-2010 Taiwanese National Health Insurance Research Database to identify cases of PD in the year 2000 matching (1:1) with persons without PD during 1999-2000 according to sex and individual age as the control group. Using Cox proportional regression analysis adjusting for potential confounders, including age, sex, and comorbidities at baseline, and average annual number of ambulatory visits and dental scaling frequency during the follow-up period, we estimated hazard ratios (HRs) with 95% confidence intervals (CIs) to examine the risk of atrial fibrillation or flutter in PD patients in comparison with the control group. Subgroup analyses according to age, gender, or comorbidities were conducted to study the robustness of the association and investigate possible interaction effects.
We enrolled 393,745 patients with PD and 393,745 non-PD individuals. The incidence rates of atrial fibrillation or flutter were 200 per 105 years among the PD group and 181 per 105 years in the non-PD group (incidence rate ratio, 1.10; 95% CI, 1.06-1.14). After adjusting for potential confounders, we found an increased risk of atrial fibrillation or flutter in the PD group compared with the non-PD group (HR, 1.31; 95% CI, 1.25-1.36). The greater risk of atrial fibrillation or flutter in the PD group remained significant across all disease subgroups except hyperthyroidism and sleep apnea.
The present study results indicate an increased risk of atrial fibrillation or flutter in patients with PD. Lack of individual information about alcohol consumption, obesity, and tobacco use was a major limitation.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0165601</identifier><identifier>PMID: 27798703</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Aged ; Aged, 80 and over ; Alcohols ; Ambulatory care ; Apnea ; Atrial fibrillation ; Atrial Fibrillation - epidemiology ; Atrial Fibrillation - etiology ; Atrial Flutter - epidemiology ; Atrial Flutter - etiology ; Cardiac arrhythmia ; Cardiology ; Chronic obstructive pulmonary disease ; Cohort analysis ; Cohort Studies ; Comorbidity ; Confidence intervals ; Electrocardiography ; Female ; Fibrillation ; Flutter ; Gender ; Gum disease ; Health care ; Health education ; Heart ; Hospitals ; Humans ; Hyperthyroidism ; Hypothyroidism ; Immunology ; Incidence ; Inflammation ; Internal medicine ; Kidney diseases ; Male ; Medical research ; Medicine and Health Sciences ; Middle Aged ; National health insurance ; Online databases ; Patients ; Periodontitis ; Periodontitis - complications ; Periodontitis - epidemiology ; Population ; Population studies ; Population Surveillance ; Population-based studies ; Preventive medicine ; Proportional Hazards Models ; Regression analysis ; Retrospective Studies ; Rheumatology ; Risk ; Scaling ; Sex ; Sleep ; Sleep apnea ; Sleep disorders ; Smoking ; Statistical analysis ; Studies ; Subgroups ; Taiwan - epidemiology ; Tobacco ; Vibration</subject><ispartof>PloS one, 2016-10, Vol.11 (10), p.e0165601-e0165601</ispartof><rights>COPYRIGHT 2016 Public Library of Science</rights><rights>2016 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2016 Chen et al 2016 Chen et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c795t-93546d05acb8923b250efe004d8106aa682a046e4ac15d7b08d917bb1bf98abf3</citedby><cites>FETCH-LOGICAL-c795t-93546d05acb8923b250efe004d8106aa682a046e4ac15d7b08d917bb1bf98abf3</cites><orcidid>0000-0002-7304-4587</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087888/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087888/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,729,782,786,866,887,2104,2930,23873,27931,27932,53798,53800</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27798703$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Talkachova, Alena</contributor><creatorcontrib>Chen, Der-Yuan</creatorcontrib><creatorcontrib>Lin, Ching-Heng</creatorcontrib><creatorcontrib>Chen, Yi-Ming</creatorcontrib><creatorcontrib>Chen, Hsin-Hua</creatorcontrib><title>Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To investigate the risk of atrial fibrillation or atrial flutter in patients with periodontitis (PD) in comparison with individuals without PD.
We used the 1999-2010 Taiwanese National Health Insurance Research Database to identify cases of PD in the year 2000 matching (1:1) with persons without PD during 1999-2000 according to sex and individual age as the control group. Using Cox proportional regression analysis adjusting for potential confounders, including age, sex, and comorbidities at baseline, and average annual number of ambulatory visits and dental scaling frequency during the follow-up period, we estimated hazard ratios (HRs) with 95% confidence intervals (CIs) to examine the risk of atrial fibrillation or flutter in PD patients in comparison with the control group. Subgroup analyses according to age, gender, or comorbidities were conducted to study the robustness of the association and investigate possible interaction effects.
We enrolled 393,745 patients with PD and 393,745 non-PD individuals. The incidence rates of atrial fibrillation or flutter were 200 per 105 years among the PD group and 181 per 105 years in the non-PD group (incidence rate ratio, 1.10; 95% CI, 1.06-1.14). After adjusting for potential confounders, we found an increased risk of atrial fibrillation or flutter in the PD group compared with the non-PD group (HR, 1.31; 95% CI, 1.25-1.36). The greater risk of atrial fibrillation or flutter in the PD group remained significant across all disease subgroups except hyperthyroidism and sleep apnea.
The present study results indicate an increased risk of atrial fibrillation or flutter in patients with PD. Lack of individual information about alcohol consumption, obesity, and tobacco use was a major limitation.</description><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alcohols</subject><subject>Ambulatory care</subject><subject>Apnea</subject><subject>Atrial fibrillation</subject><subject>Atrial Fibrillation - epidemiology</subject><subject>Atrial Fibrillation - etiology</subject><subject>Atrial Flutter - epidemiology</subject><subject>Atrial Flutter - etiology</subject><subject>Cardiac arrhythmia</subject><subject>Cardiology</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>Confidence intervals</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Fibrillation</subject><subject>Flutter</subject><subject>Gender</subject><subject>Gum disease</subject><subject>Health care</subject><subject>Health education</subject><subject>Heart</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hyperthyroidism</subject><subject>Hypothyroidism</subject><subject>Immunology</subject><subject>Incidence</subject><subject>Inflammation</subject><subject>Internal medicine</subject><subject>Kidney diseases</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>National health insurance</subject><subject>Online databases</subject><subject>Patients</subject><subject>Periodontitis</subject><subject>Periodontitis - complications</subject><subject>Periodontitis - epidemiology</subject><subject>Population</subject><subject>Population studies</subject><subject>Population Surveillance</subject><subject>Population-based studies</subject><subject>Preventive medicine</subject><subject>Proportional Hazards Models</subject><subject>Regression analysis</subject><subject>Retrospective Studies</subject><subject>Rheumatology</subject><subject>Risk</subject><subject>Scaling</subject><subject>Sex</subject><subject>Sleep</subject><subject>Sleep apnea</subject><subject>Sleep disorders</subject><subject>Smoking</subject><subject>Statistical analysis</subject><subject>Studies</subject><subject>Subgroups</subject><subject>Taiwan - epidemiology</subject><subject>Tobacco</subject><subject>Vibration</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1tv0zAYhiMEYmPwDxBYQkIgrcWHOHa4QCoVhUoTmzbg1nJsp3WXxsV2GPv3OGs2tWgXUy4c28_72v4OWfYSwTEiDH1Yuc63shlvXGvGEBW0gOhRdohKgkcFhuTxzv9B9iyEFYSU8KJ4mh1gxkrOIDnM_LkNl8DVYBK9lQ2Y2crbppHRuhY4D2ZNF6PxYBKCU1ZGo8GVjUtwZrx12rXRRhs-ggn4fiO5stocgzO36bYWo88yGH0Mpm7pfAQXsdPXz7MntWyCeTGMR9nP2Zcf02-jk9Ov8-nkZKRYSeOoJDQvNKRSVbzEpMIUmtpAmGuOYCFlwbGEeWFyqRDVrIJcl4hVFarqksuqJkfZ663vpnFBDOEKAnGSE44xo4mYbwnt5EpsvF1Lfy2ctOJmwfmFkD5a1RiRc80Zz2mlsMplraRUXJE8TYlhyPDk9Wk4ravWRivTRi-bPdP9ndYuxcL9ERQmY94bvBsMvPvdmRDF2gZlUi5a47r-3nlBSkYpfgBKKIQYFyihb_5D7w_EQC1keqtta5euqHpTMckZYiXkqPca30OlT5u1VakMa5vW9wTv9wSJieZvXMguBDG_OH84e_prn327wy6NbOIyuFSpqeLCPphvQeVdCN7Ud_lAUPRddBsN0XeRGLooyV7t5vJOdNs25B8EQBd3</recordid><startdate>20161031</startdate><enddate>20161031</enddate><creator>Chen, Der-Yuan</creator><creator>Lin, Ching-Heng</creator><creator>Chen, Yi-Ming</creator><creator>Chen, Hsin-Hua</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7304-4587</orcidid></search><sort><creationdate>20161031</creationdate><title>Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study</title><author>Chen, Der-Yuan ; Lin, Ching-Heng ; Chen, Yi-Ming ; Chen, Hsin-Hua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c795t-93546d05acb8923b250efe004d8106aa682a046e4ac15d7b08d917bb1bf98abf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alcohols</topic><topic>Ambulatory care</topic><topic>Apnea</topic><topic>Atrial fibrillation</topic><topic>Atrial Fibrillation - epidemiology</topic><topic>Atrial Fibrillation - etiology</topic><topic>Atrial Flutter - epidemiology</topic><topic>Atrial Flutter - etiology</topic><topic>Cardiac arrhythmia</topic><topic>Cardiology</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Confidence intervals</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Fibrillation</topic><topic>Flutter</topic><topic>Gender</topic><topic>Gum disease</topic><topic>Health care</topic><topic>Health education</topic><topic>Heart</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hyperthyroidism</topic><topic>Hypothyroidism</topic><topic>Immunology</topic><topic>Incidence</topic><topic>Inflammation</topic><topic>Internal medicine</topic><topic>Kidney diseases</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>National health insurance</topic><topic>Online databases</topic><topic>Patients</topic><topic>Periodontitis</topic><topic>Periodontitis - complications</topic><topic>Periodontitis - epidemiology</topic><topic>Population</topic><topic>Population studies</topic><topic>Population Surveillance</topic><topic>Population-based studies</topic><topic>Preventive medicine</topic><topic>Proportional Hazards Models</topic><topic>Regression analysis</topic><topic>Retrospective Studies</topic><topic>Rheumatology</topic><topic>Risk</topic><topic>Scaling</topic><topic>Sex</topic><topic>Sleep</topic><topic>Sleep apnea</topic><topic>Sleep disorders</topic><topic>Smoking</topic><topic>Statistical analysis</topic><topic>Studies</topic><topic>Subgroups</topic><topic>Taiwan - epidemiology</topic><topic>Tobacco</topic><topic>Vibration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Der-Yuan</creatorcontrib><creatorcontrib>Lin, Ching-Heng</creatorcontrib><creatorcontrib>Chen, Yi-Ming</creatorcontrib><creatorcontrib>Chen, Hsin-Hua</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Der-Yuan</au><au>Lin, Ching-Heng</au><au>Chen, Yi-Ming</au><au>Chen, Hsin-Hua</au><au>Talkachova, Alena</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2016-10-31</date><risdate>2016</risdate><volume>11</volume><issue>10</issue><spage>e0165601</spage><epage>e0165601</epage><pages>e0165601-e0165601</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To investigate the risk of atrial fibrillation or atrial flutter in patients with periodontitis (PD) in comparison with individuals without PD.
We used the 1999-2010 Taiwanese National Health Insurance Research Database to identify cases of PD in the year 2000 matching (1:1) with persons without PD during 1999-2000 according to sex and individual age as the control group. Using Cox proportional regression analysis adjusting for potential confounders, including age, sex, and comorbidities at baseline, and average annual number of ambulatory visits and dental scaling frequency during the follow-up period, we estimated hazard ratios (HRs) with 95% confidence intervals (CIs) to examine the risk of atrial fibrillation or flutter in PD patients in comparison with the control group. Subgroup analyses according to age, gender, or comorbidities were conducted to study the robustness of the association and investigate possible interaction effects.
We enrolled 393,745 patients with PD and 393,745 non-PD individuals. The incidence rates of atrial fibrillation or flutter were 200 per 105 years among the PD group and 181 per 105 years in the non-PD group (incidence rate ratio, 1.10; 95% CI, 1.06-1.14). After adjusting for potential confounders, we found an increased risk of atrial fibrillation or flutter in the PD group compared with the non-PD group (HR, 1.31; 95% CI, 1.25-1.36). The greater risk of atrial fibrillation or flutter in the PD group remained significant across all disease subgroups except hyperthyroidism and sleep apnea.
The present study results indicate an increased risk of atrial fibrillation or flutter in patients with PD. Lack of individual information about alcohol consumption, obesity, and tobacco use was a major limitation.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>27798703</pmid><doi>10.1371/journal.pone.0165601</doi><tpages>e0165601</tpages><orcidid>https://orcid.org/0000-0002-7304-4587</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | PloS one, 2016-10, Vol.11 (10), p.e0165601-e0165601 |
| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Age Aged Aged, 80 and over Alcohols Ambulatory care Apnea Atrial fibrillation Atrial Fibrillation - epidemiology Atrial Fibrillation - etiology Atrial Flutter - epidemiology Atrial Flutter - etiology Cardiac arrhythmia Cardiology Chronic obstructive pulmonary disease Cohort analysis Cohort Studies Comorbidity Confidence intervals Electrocardiography Female Fibrillation Flutter Gender Gum disease Health care Health education Heart Hospitals Humans Hyperthyroidism Hypothyroidism Immunology Incidence Inflammation Internal medicine Kidney diseases Male Medical research Medicine and Health Sciences Middle Aged National health insurance Online databases Patients Periodontitis Periodontitis - complications Periodontitis - epidemiology Population Population studies Population Surveillance Population-based studies Preventive medicine Proportional Hazards Models Regression analysis Retrospective Studies Rheumatology Risk Scaling Sex Sleep Sleep apnea Sleep disorders Smoking Statistical analysis Studies Subgroups Taiwan - epidemiology Tobacco Vibration |
| title | Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-03T22%3A39%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Risk%20of%20Atrial%20Fibrillation%20or%20Flutter%20Associated%20with%20Periodontitis:%20A%20Nationwide,%20Population-Based,%20Cohort%20Study&rft.jtitle=PloS%20one&rft.au=Chen,%20Der-Yuan&rft.date=2016-10-31&rft.volume=11&rft.issue=10&rft.spage=e0165601&rft.epage=e0165601&rft.pages=e0165601-e0165601&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0165601&rft_dat=%3Cgale_plos_%3EA471790811%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1834382275&rft_id=info:pmid/27798703&rft_galeid=A471790811&rft_doaj_id=oai_doaj_org_article_48d87845bc2c4afcaac8c34bc23e71e8&rfr_iscdi=true |