New Assays to Characterise Growth-Related Phenotypes of Plasmodium falciparum Reveal Variation in Density-Dependent Growth Inhibition between Parasite Lines

The growth phenotype of asexual blood stage malaria parasites can influence their virulence and also their ability to survive and achieve transmission to the next host, but there are few methods available to characterise parasite growth parameters in detail. We developed a new assay to measure growt...

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Veröffentlicht in:	PloS one 2016-10, Vol.11 (10), p.e0165358-e0165358
Hauptverfasser:	Rovira-Graells, Núria, Aguilera-Simón, Sara, Tintó-Font, Elisabet, Cortés, Alfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Biology and Life Sciences Blood Cell cycle Cytometry Density Disease transmission Erythrocytes Erythrocytes - parasitology Flow Cytometry Gene deletion Genetic aspects Genomics Growth Growth rate Humans Inhibition Life Cycle Stages Malalties parasitàries Malaria Malaria, Falciparum - diagnosis Malaria, Falciparum - parasitology Medicine and Health Sciences Merozoites - physiology Microarray Analysis Parameter identification Parasitemia - diagnosis Parasitemia - parasitology Parasites Parasitic diseases Phenotype Phenotypes Plasmodium falciparum Plasmodium falciparum - growth & development Plasmodium falciparum - physiology Proteomics Research and Analysis Methods Schizonts - growth & development Variation Vector-borne diseases Virulence Virulence (Microbiology)
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