Responses of Bovine Innate Immunity to Mycobacterium avium subsp. paratuberculosis Infection Revealed by Changes in Gene Expression and Levels of MicroRNA

Paratuberculosis in cattle is a chronic granulomatous gastroenteritis caused by Mycobacterium avium subsp. paratubercolosis (MAP) which is endemic worldwide. In dairy herds, it is responsible for huge economic losses. However, current diagnostic methods do not detect subclinical infection making con...

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Veröffentlicht in:	PloS one 2016-10, Vol.11 (10), p.e0164461-e0164461
Hauptverfasser:	Malvisi, Michela, Palazzo, Fiorentina, Morandi, Nicola, Lazzari, Barbara, Williams, John L, Pagnacco, Giulio, Minozzi, Giulietta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Bioinformatics Biology and life sciences Biomarkers Biomarkers - blood Biomarkers - metabolism Bovidae Cattle Cattle Diseases - blood Cattle Diseases - genetics Cattle Diseases - immunology Dairy cattle Dairying Diagnosis Diagnostic systems Disease control Economic impact Enzyme-linked immunosorbent assay Exposure Gastroenteritis Gene expression Gene Expression Profiling Gene Regulatory Networks Genes Health aspects Immunity Immunity, Innate Infection Infections Inflammation Inflammatory response Innate immunity Johne's disease Lipid metabolism Medicine and Health Sciences Metabolism MicroRNA MicroRNAs MicroRNAs - blood miRNA Mycobacterium avium Mycobacterium avium subsp. paratuberculosis - physiology Paratuberculosis Paratuberculosis - blood Paratuberculosis - genetics Paratuberculosis - immunology Research and Analysis Methods Ribonucleic acid RNA Subclinical infection Veterinary medicine
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