Differential Activation Patterns in the Same Brain Region Led to Opposite Emotional States
In human studies, how averaged activation in a brain region relates to human behavior has been extensively investigated. This approach has led to the finding that positive and negative facial preferences are represented by different brain regions. However, using a functional magnetic resonance imagi...
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| Veröffentlicht in: | PLoS biology 2016-09, Vol.14 (9), p.e1002546-e1002546 |
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| creator | Shibata, Kazuhisa Watanabe, Takeo Kawato, Mitsuo Sasaki, Yuka |
| description | In human studies, how averaged activation in a brain region relates to human behavior has been extensively investigated. This approach has led to the finding that positive and negative facial preferences are represented by different brain regions. However, using a functional magnetic resonance imaging (fMRI) decoded neurofeedback (DecNef) method, we found that different patterns of neural activations within the cingulate cortex (CC) play roles in representing opposite directions of facial preference. In the present study, while neutrally preferred faces were presented, multi-voxel activation patterns in the CC that corresponded to higher (or lower) preference were repeatedly induced by fMRI DecNef. As a result, previously neutrally preferred faces became more (or less) preferred. We conclude that a different activation pattern in the CC, rather than averaged activation in a different area, represents and suffices to determine positive or negative facial preference. This new approach may reveal the importance of an activation pattern within a brain region in many cognitive functions. |
| doi_str_mv | 10.1371/journal.pbio.1002546 |
| format | Article |
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This approach has led to the finding that positive and negative facial preferences are represented by different brain regions. However, using a functional magnetic resonance imaging (fMRI) decoded neurofeedback (DecNef) method, we found that different patterns of neural activations within the cingulate cortex (CC) play roles in representing opposite directions of facial preference. In the present study, while neutrally preferred faces were presented, multi-voxel activation patterns in the CC that corresponded to higher (or lower) preference were repeatedly induced by fMRI DecNef. As a result, previously neutrally preferred faces became more (or less) preferred. We conclude that a different activation pattern in the CC, rather than averaged activation in a different area, represents and suffices to determine positive or negative facial preference. 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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Shibata K, Watanabe T, Kawato M, Sasaki Y (2016) Differential Activation Patterns in the Same Brain Region Led to Opposite Emotional States. PLoS Biol 14(9): e1002546. doi:10.1371/journal.pbio.1002546</rights><rights>2016 Shibata et al 2016 Shibata et al</rights><rights>2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Shibata K, Watanabe T, Kawato M, Sasaki Y (2016) Differential Activation Patterns in the Same Brain Region Led to Opposite Emotional States. 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This approach has led to the finding that positive and negative facial preferences are represented by different brain regions. However, using a functional magnetic resonance imaging (fMRI) decoded neurofeedback (DecNef) method, we found that different patterns of neural activations within the cingulate cortex (CC) play roles in representing opposite directions of facial preference. In the present study, while neutrally preferred faces were presented, multi-voxel activation patterns in the CC that corresponded to higher (or lower) preference were repeatedly induced by fMRI DecNef. As a result, previously neutrally preferred faces became more (or less) preferred. We conclude that a different activation pattern in the CC, rather than averaged activation in a different area, represents and suffices to determine positive or negative facial preference. 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| subjects | Adult Biology and Life Sciences Brain - physiology Brain research Cognitive ability Emotions - physiology Engineering and Technology Female Humans Information communication Laboratories Linguistics Magnetic Resonance Imaging Male Medicine and Health Sciences Methods Neural circuitry NMR Nuclear magnetic resonance Physical Sciences Physiological aspects Preferences R&D Research & development Research and Analysis Methods Science Social Sciences Studies Young Adult |
| title | Differential Activation Patterns in the Same Brain Region Led to Opposite Emotional States |
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