Impact of TIEG1 Deletion on the Passive Mechanical Properties of Fast and Slow Twitch Skeletal Muscles in Female Mice

As transforming growth factor (TGF)-β inducible early gene-1 is highly expressed in skeletal muscle, the effect of TIEG1 gene deletion on the passive mechanical properties of slow and fast twitch muscle fibers was analyzed. Twenty five muscle fibers were harvested from soleus (Sol) and extensor digi...

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Veröffentlicht in:	PloS one 2016-10, Vol.11 (10), p.e0164566
Hauptverfasser:	Kammoun, Malek, Pouletaut, Philippe, Canon, Francis, Subramaniam, Malayannan, Hawse, John R, Vayssade, Muriel, Bensamoun, Sabine F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal biology Animals Biochemistry Biochemistry, Molecular Biology Bioengineering Biology and Life Sciences Biomechanical Phenomena biomechanical phenomena/methods Biomechanics Clonal deletion Computer Science Data processing DNA-Binding Proteins - genetics Engineering Sciences Female Fibers Gene Deletion Genotypes Glycerol Glycolysis Growth factors Histology Human health and pathology Hypertrophy Isoforms Laboratories Life Sciences Mechanical properties Mechanical tests Mechanics Medicine and Health Sciences Mice Modeling and Simulation Models, Biological Molecular biology Muscle Fibers, Fast-Twitch - pathology Muscle Fibers, Slow-Twitch - pathology Muscle proteins Muscle, Skeletal - pathology Muscle, Skeletal - physiopathology Muscles Musculoskeletal system Myosin NMR Nuclear magnetic resonance Physiology Research and Analysis Methods Rodents Skeletal muscle Skeletal Muscle Myosins - metabolism Stress, Mechanical Tissues and Organs Transcription Factors - genetics Transforming growth factor Transforming growth factors Viscoelasticity
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