Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats

Intermittent alcohol exposure is a common pattern of alcohol consumption among adolescents and alcohol is known to modulate the expression of the endocannabinoid system (ECS), which is involved in metabolism and inflammation. However, it is unknown whether this pattern may have short-term consequenc...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0163752-e0163752
Hauptverfasser:	Pavón, Francisco Javier, Marco, Eva María, Vázquez, Mariam, Sánchez, Laura, Rivera, Patricia, Gavito, Ana, Mela, Virginia, Alén, Francisco, Decara, Juan, Suárez, Juan, Giné, Elena, López-Moreno, José Antonio, Chowen, Julie, Rodríguez-de-Fonseca, Fernando, Serrano, Antonia, Viveros, María Paz
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Alcohol use Alcoholic beverages Alcoholism Biology and Life Sciences Cannabinoid CB2 receptors Chemokines Cocaine Cytokines Drinking (Alcoholic beverages) Drinking behavior Endocannabinoid system Enzymes Exposure Fatty acids Fractalkine Gender differences Gene expression Glycerol Hospitals Immune system Inflammation Interleukin 6 Interleukins Juvenile drinking Liver Medicine and Health Sciences Metabolism mRNA Phosphatidylethanolamine Phospholipase Phospholipase D Physical Sciences Proteins Rats Receptors RNA Rodents Sex Sexual dimorphism Signaling Spleen Teenagers Tumor necrosis factor-TNF Tumor necrosis factor-α Young adults Youth
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