Righting Reflex Predicts Long-Term Histological and Behavioral Outcomes in a Closed Head Model of Traumatic Brain Injury

Blunt impact produces a heterogeneous brain injury in people and in animal models of traumatic brain injury. We report that a single closed head impact to adult C57/BL6 mice produced two injury syndromes (CHI-1 and CHI-2). CHI-1 mice spontaneously reinitiated breathing after injury while CHI-2 mice...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0161053-e0161053
Hauptverfasser:	Grin'kina, Natalia M, Li, Yang, Haber, Margalit, Sangobowale, Michael, Nikulina, Elena, Le'Pre, Charm, El Sehamy, Alexander M, Dugue, Rachelle, Ho, Johnson S, Bergold, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Apnea Axons Behavioral sciences Biology and Life Sciences Brain Brain injuries Breathing Cognition & reasoning Furchgott, Robert F Head Head injuries Hippocampus Impact analysis Medicine and Health Sciences Mice Myelin Neurons Pharmacology Physiological responses Physiology Prognosis Research and Analysis Methods Respiration Resuscitation Righting reflex Rodents Substantia alba Trauma Traumatic brain injury Vertical forces
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