Adverse Renal, Endocrine, Hepatic, and Metabolic Events during Maintenance Mood Stabilizer Treatment for Bipolar Disorder: A Population-Based Cohort Study

There is limited, poorly characterized information about adverse events occurring during maintenance treatment of bipolar disorder. We aimed to determine adverse event rates during treatment with lithium, valproate, olanzapine, and quetiapine. We conducted a propensity score adjusted cohort study us...

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Veröffentlicht in:	PLoS medicine 2016-08, Vol.13 (8), p.e1002058
Hauptverfasser:	Hayes, Joseph F, Marston, Louise, Walters, Kate, Geddes, John R, King, Michael, Osborn, David P J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Antidepressants Antipsychotic Agents - adverse effects Antipsychotic Agents - therapeutic use Benzodiazepines - adverse effects Benzodiazepines - therapeutic use Biology and Life Sciences Bipolar disorder Bipolar Disorder - drug therapy Cardiovascular disease Cardiovascular Diseases - chemically induced Chemical and Drug Induced Liver Injury - etiology Chronic kidney failure Cohort Studies Collaboration Complications and side effects Confidence intervals Diabetes Diabetes Mellitus, Type 2 - chemically induced Dosage and administration Drug therapy Family medicine Female Humans Hypercalcemia - chemically induced Hypertension Hypertension - chemically induced Kidney diseases Lithium Compounds - adverse effects Lithium Compounds - therapeutic use Longitudinal Studies Male Management Medicine and Health Sciences Metabolism Middle Aged Olanzapine Patients Physical Sciences Physiology Primary care Primary health care Propensity Score Quetiapine Fumarate - adverse effects Quetiapine Fumarate - therapeutic use Renal Insufficiency - chemically induced Research and Analysis Methods Studies Substance abuse treatment Thyroid diseases Thyroid Diseases - chemically induced Type 2 diabetes Valproic Acid - adverse effects Valproic Acid - therapeutic use
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