The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina

Alternative pre-mRNA splicing expands the coding capacity of eukaryotic genomes, potentially enabling a limited number of genes to govern the development of complex anatomical structures. Alternative splicing is particularly prevalent in the vertebrate nervous system, where it is required for neuron...

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Veröffentlicht in:	PLoS genetics 2016-08, Vol.12 (8), p.e1006256-e1006256
Hauptverfasser:	Murphy, Daniel, Cieply, Benjamin, Carstens, Russ, Ramamurthy, Visvanathan, Stoilov, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - genetics Amino Acid Sequence Animals Binding sites Biology and Life Sciences Biosynthesis Exons (Molecular genetics) Exons - genetics Funding Gene expression Gene Expression Regulation, Developmental Genetic aspects Genetic regulation Genetic research Genomes Genomics Grants Light Medicine and Health Sciences Mice Morphology Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - genetics Nervous system Neurons Photoreceptor Cells - metabolism Photoreceptors Protein Isoforms - biosynthesis Protein Isoforms - genetics Proteins Research and Analysis Methods Retina Retina - growth & development Retina - metabolism RNA splicing RNA-Binding Proteins - biosynthesis RNA-Binding Proteins - genetics Sensory Receptor Cells - metabolism Social Sciences Vertebrates Vertebrates - genetics Vertebrates - growth & development
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