Multiparametric Functional MRI: Non-Invasive Imaging of Inflammation and Edema Formation after Kidney Transplantation in Mice

Kidney transplantation (ktx) in mice is used to learn about rejection and to develop new treatment strategies. Past studies have mainly been based on histological or molecular biological methods. Imaging techniques to monitor allograft pathology have rarely been used. Here we investigated mice after...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0162705-e0162705
Hauptverfasser:	Hueper, Katja, Gutberlet, Marcel, Bräsen, Jan Hinrich, Jang, Mi-Sun, Thorenz, Anja, Chen, Rongjun, Hertel, Barbara, Barrmeyer, Amelie, Schmidbauer, Martina, Meier, Martin, von Vietinghoff, Sibylle, Khalifa, Abedalrazag, Hartung, Dagmar, Haller, Hermann, Wacker, Frank, Rong, Song, Gueler, Faikah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal sciences Animals Biology and Life Sciences CD3 antigen Coronary vessels Cytometry Diffusion Driving while intoxicated Edema Edema - diagnostic imaging Flow cytometry Functional magnetic resonance imaging Graft rejection Grafting Grafts Imaging techniques Infiltration Inflammation Inflammation - diagnostic imaging Ischemia Kidney diseases Kidney Transplantation Kidney transplants Laboratory animals Leukocytes Lymphocytes Lymphocytes T Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Mapping Medical research Medical schools Medicine and Health Sciences Mice Mice, Inbred C57BL Moisture content Nephrology Neuroimaging NMR Nuclear magnetic resonance Pathology Physiology Rejection Relaxation time Renal cortex Renal function Research and Analysis Methods Rodents Studies Transplantation Transplants & implants Water chemistry Water content Zoology
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