Profiling of Small Nucleolar RNAs by Next Generation Sequencing: Potential New Players for Breast Cancer Prognosis

One of the most abundant, yet least explored, classes of RNA is the small nucleolar RNAs (snoRNAs), which are well known for their involvement in post-transcriptional modifications of other RNAs. Although snoRNAs were only considered to perform housekeeping functions for a long time, recent studies...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0162622-e0162622
Hauptverfasser:	Krishnan, Preethi, Ghosh, Sunita, Wang, Bo, Heyns, Mieke, Graham, Kathryn, Mackey, John R, Kovalchuk, Olga, Damaraju, Sambasivarao
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and life sciences Biomarkers Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Cancer research Colorectal cancer Diagnostic systems Ethics Female Gene expression Gene sequencing Genes Genomes Genomics Hazards Health services High-Throughput Nucleotide Sequencing Humans Laboratories Markers Medical prognosis Medical research MicroRNAs miRNA Nucleoli Oncology Pathology Permutations Post-transcription Prognosis Proportional Hazards Models Proteins Quality of life Regression analysis Regression models Regulators Research and analysis methods Ribonucleic acid Risk Risk groups RNA RNA sequencing RNA, Small Nucleolar - genetics snoRNA Survival Tissues Transcription (Genetics) Tumorigenesis
Online-Zugang:	Volltext
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