Altered Resting-State Functional Connectivity of the Striatum in Parkinson's Disease after Levodopa Administration

Despite improvement in motor symptoms, the effect of dopaminergic medications on cognition in patients with Parkinson's disease (PD) is less clear. The purpose of this study was to reveal levodopa-induced acute changes in the functional connectivity of the striatum in patients with PD compared...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0161935-e0161935
Hauptverfasser:	Yang, Wanqun, Liu, Bin, Huang, Biao, Huang, Ruiwang, Wang, Lijuan, Zhang, Yuhu, Zhang, Xiong, Wu, Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Biology and Life Sciences Brain research Cognition Cognition & reasoning Cognition - drug effects Cognitive ability Comparative analysis Connectivity Corpus Striatum - drug effects Corpus Striatum - physiology Cortex (cingulate) Cortex (parietal) Dementia Diagnostic imaging Dopamine Dopamine receptors Female Functional magnetic resonance imaging Healthy Volunteers Hospitals Humans L-dopa Levodopa Levodopa - pharmacology Levodopa - therapeutic use Magnetic resonance Magnetic Resonance Imaging Male Medical research Medicine and Health Sciences Middle Aged Movement disorders Neostriatum Neural Pathways - drug effects Neurodegenerative diseases Neuroimaging Neurology Neurosciences NMR Nuclear magnetic resonance Older people Parahippocampal gyrus Parkinson Disease - metabolism Parkinson's disease Parkinsons disease Patients Physical Sciences Prefrontal cortex Putamen Putamen - drug effects Putamen - physiology Research and Analysis Methods Science Seeds Therapy
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