Stability and Species Specificity of Renal VEGF-A Splicing Patterns in Kidney Disease

Vascular endothelial growth factor A (VEGF-A) is essential for maintaining the glomerular filtration barrier. Absolute renal levels of VEGF-A change in patients with diabetic nephropathy and inflammatory kidney diseases, but whether changes in the renal splicing patterns of VEGF-A play a role remain...

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Veröffentlicht in:	PloS one 2016-09, Vol.11 (9), p.e0162166-e0162166
Hauptverfasser:	Turner, R J, Eikmans, M, Bajema, I M, Bruijn, J A, Baelde, H J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Analysis Angiogenesis Animal models Animals Autoimmune diseases Binding sites Biological activity Biology and Life Sciences Biopsy Case-Control Studies Control stability Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - pathology Diabetes Mellitus, Type 2 - surgery Diabetic Nephropathies - genetics Diabetic Nephropathies - metabolism Diabetic Nephropathies - pathology Diabetic Nephropathies - surgery Diabetic nephropathy Disease control Disease Models, Animal Disease Progression Gene Expression Genetic aspects Graft rejection Graft Rejection - genetics Graft Rejection - immunology Graft Rejection - pathology Health aspects Humans Identification and classification Isoforms Kidney diseases Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Kidney Transplantation Lupus Lupus nephritis Lupus Nephritis - genetics Lupus Nephritis - metabolism Lupus Nephritis - pathology Medicine and Health Sciences Mice mRNA Nephritis Nephropathy Pathology Patients Polymerase chain reaction Rejection Research and Analysis Methods Rodents Species Specificity Studies Transplantation Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
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