Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing

Malignant gliomas are aggressive brain tumours with very poor prognosis. The majority of glioma cells are differentiated (glioma-differentiated cells: GDCs), whereas the smaller population (glioma-initiating cells, GICs) is undifferentiated and resistant to conventional therapies. Therefore, to bett...

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Veröffentlicht in:PloS one 2016-08, Vol.11 (8), p.e0162105-e0162105
Hauptverfasser: Riccadonna, Cristina, Yacoub Maroun, Céline, Vuillefroy de Silly, Romain, Boehler, Margaux, Calvo Tardón, Marta, Jueliger, Simone, Taverna, Pietro, Barba, Leticia, Marinari, Eliana, Pellegatta, Serena, Bassoy, Esen Yonca, Martinvalet, Denis, Dietrich, Pierre-Yves, Walker, Paul R
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Sprache:eng
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