The Selector Gene apterous and Notch Are Required to Locally Increase Mechanical Cell Bond Tension at the Drosophila Dorsoventral Compartment Boundary

The separation of cells with distinct fates and functions is important for tissue and organ formation during animal development. Regions of different fates within tissues are often separated from another along straight boundaries. These compartment boundaries play a crucial role in tissue patterning...

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Veröffentlicht in:	PloS one 2016-08, Vol.11 (8), p.e0161668-e0161668
Hauptverfasser:	Michel, Marcus, Aliee, Maryam, Rudolf, Katrin, Bialas, Lisa, Jülicher, Frank, Dahmann, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal wings Animals Biology and Life Sciences Body Patterning - genetics Borders Boundaries Cell adhesion & migration Cell division Computer simulation Drosophila Drosophila - anatomy & histology Drosophila - embryology Drosophila - physiology Drosophila Proteins - genetics Drosophila Proteins - metabolism Engineering and Technology Gene expression Gene Expression Regulation, Developmental Genetic aspects Image analysis Image processing Insects Kinases Laser ablation Ligands Mechanical Phenomena Models, Theoretical Mutants Notch protein Pattern formation Physical Sciences Physiological aspects Receptors, Notch - genetics Receptors, Notch - metabolism Research and Analysis Methods Selection, Genetic Separation Signal Transduction Signaling Stress, Mechanical Tension Tissues
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