Analysis of the Trypanosoma brucei EATRO 164 Bloodstream Guide RNA Transcriptome

The mitochondrial genome of Trypanosoma brucei contains many cryptogenes that must be extensively edited following transcription. The RNA editing process is directed by guide RNAs (gRNAs) that encode the information for the specific insertion and deletion of uridylates required to generate translata...

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Veröffentlicht in:	PLoS neglected tropical diseases 2016-07, Vol.10 (7), p.e0004793-e0004793
Hauptverfasser:	Kirby, Laura E, Sun, Yanni, Judah, David, Nowak, Scooter, Koslowsky, Donna
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biology and Life Sciences Cytochrome Dehydrogenases Editing Gene expression Gene Expression Regulation - physiology Genetic aspects Genome, Mitochondrial Genomes Health aspects Life cycles Methods Mitochondrial DNA Mutation Proteins Protozoan Proteins - genetics Protozoan Proteins - metabolism Research and analysis methods RNA Editing RNA sequencing RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Protozoan - genetics RNA, Protozoan - metabolism Transcription (Genetics) Transcriptome - genetics Tropical diseases Trypanosoma Trypanosoma brucei brucei - genetics Trypanosoma brucei brucei - metabolism
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