Efficacy Assessment of Nucleic Acid Decontamination Reagents Used in Molecular Diagnostic Laboratories

The occurrence of nucleic acid cross contamination in the laboratory resulting in false positive results of diagnostic samples is seriously problematic. Despite precautions to minimize or even avoid nucleic acid cross contaminations, it may appear anyway. Until now, no standardized strategy is avail...

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Veröffentlicht in:	PloS one 2016-07, Vol.11 (7), p.e0159274-e0159274
Hauptverfasser:	Fischer, Melina, Renevey, Nathalie, Thür, Barbara, Hoffmann, Donata, Beer, Martin, Hoffmann, Bernd
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Biology and Life Sciences Chemical reduction Contamination Decontamination Decontamination - methods Deoxyribonucleic acid Diagnostic systems Disinfection & disinfectants DNA DNA - metabolism Effectiveness Equipment Contamination - prevention & control False Positive Reactions Immunology Laboratories Medical diagnosis Medicine and Health Sciences Molecular diagnostic techniques Nucleic acid aptamers Nucleic acids Pathology, Molecular - instrumentation Pathology, Molecular - methods Phosphoric acid Physical Sciences Polymerase chain reaction Reagents Research and Analysis Methods Ribonucleic acid RNA RNA - metabolism Sodium Sodium hydroxide Sodium Hydroxide - pharmacology Sodium hypochlorite Sodium Hypochlorite - pharmacology Technology application Test methods Virology
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