Nitrative Stress Participates in Endothelial Progenitor Cell Injury in Hyperhomocysteinemia

In order to investigate the role of nitrative stress in vascular endothelial injury in hyperhomocysteinemia (HHcy), thirty healthy adult female Wistar rats were randomly divided into three groups: control, hyperhomocysteinemia model, and hyperhomocysteinemia with FeTMPyP (peroxynitrite scavenger) tr...

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Veröffentlicht in:	PloS one 2016-07, Vol.11 (7), p.e0158672-e0158672
Hauptverfasser:	Dong, Yu, Sun, Qi, Liu, Teng, Wang, Huanyuan, Jiao, Kun, Xu, Jiahui, Liu, Xin, Liu, Huirong, Wang, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Analysis Animals Aorta Apoptosis Assaying Biology and Life Sciences Cardiovascular disease Cell injury Cells (biology) Complications and side effects Cytometry Diabetes DNA nucleotidylexotransferase Electron microscopy Endothelial Progenitor Cells - metabolism Endothelial Progenitor Cells - pathology Endothelium Female Females Flow Cytometry Homocysteine Hyperhomocysteinemia Hyperhomocysteinemia - metabolism Immunofluorescence Immunohistochemistry In Situ Nick-End Labeling Injuries L-Lactate dehydrogenase Laboratories Lactate dehydrogenase Lactic acid Medical research Medicine and Health Sciences Metabolic disorders Necrosis Nitric oxide Nitrotyrosine Peroxynitrite Physiological aspects Physiology Progenitor cells Prognosis Psychological aspects Random Allocation Rats, Wistar Research and analysis methods Rodents Scanning electron microscopy Stem cells Stress Stresses Thorax Tyrosine - analogs & derivatives Tyrosine - metabolism
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