Quantification of Diaphragm Mechanics in Pompe Disease Using Dynamic 3D MRI

Diaphragm weakness is the main reason for respiratory dysfunction in patients with Pompe disease, a progressive metabolic myopathy affecting respiratory and limb-girdle muscles. Since respiratory failure is the major cause of death among adult patients, early identification of respiratory muscle inv...

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Veröffentlicht in:	PloS one 2016-07, Vol.11 (7), p.e0158912-e0158912
Hauptverfasser:	Mogalle, Katja, Perez-Rovira, Adria, Ciet, Pierluigi, Wens, Stephan C A, van Doorn, Pieter A, Tiddens, Harm A W M, van der Ploeg, Ans T, de Bruijne, Marleen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biology and Life Sciences Breathing Care and treatment Complications and side effects Damage prevention Data processing Departments Development and progression Diaphragm Diaphragm (anatomy) Diaphragm - diagnostic imaging Diaphragm - physiopathology Disease Feature extraction Female Geometry Glycogen Storage Disease Type II - diagnostic imaging Glycogen Storage Disease Type II - physiopathology Glycogen storage diseases Health informatics Humans Image analysis Image detection Image processing Image registration Imaging, Three-Dimensional - methods Kinematics Lungs Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Mechanics (physics) Medical imaging Medical treatment Medicine Medicine and Health Sciences Metabolic disorders Middle Aged Motion perception Movement Muscles Myopathy NMR Nuclear magnetic resonance Patients Pediatrics Pulmonary functions Radiology Research and Analysis Methods Respiration Respiratory function Respiratory Mechanics Respiratory system Thorax Three dimensional imaging
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