The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression

Staphylococcus aureus is a human commensal and opportunistic pathogen that causes devastating infections in a wide range of locations within the body. One of the defining characteristics of S. aureus is its ability to form clumps in the presence of soluble fibrinogen, which likely has a protective b...

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Veröffentlicht in:	PLoS pathogens 2016-05, Vol.12 (5), p.e1005604-e1005604
Hauptverfasser:	Crosby, Heidi A, Schlievert, Patrick M, Merriman, Joseph A, King, Jessica M, Salgado-Pabón, Wilmara, Horswill, Alexander R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Bacterial Proteins - metabolism Biofilms Biology and Life Sciences Blotting, Western Care and treatment Carotid arteries Catheters Colleges & universities Disease Models, Animal Electrophoretic Mobility Shift Assay Experiments Gene expression Gene Expression Regulation, Bacterial - physiology Gene Knockdown Techniques Genomics Health aspects Medicine and Health Sciences Membrane Proteins - biosynthesis Microscopy, Electron, Scanning Microscopy, Fluorescence Mortality Pathogens Plasma Pneumonia Polymerase Chain Reaction Protein expression Protein Kinases - metabolism Proteins Rabbits Research and Analysis Methods Risk factors Skin Staphylococcal infections Staphylococcal Infections - metabolism Staphylococcus aureus Staphylococcus aureus - pathogenicity Staphylococcus infections Veins & arteries Virulence (Microbiology) Virulence - physiology Virulence Factors - metabolism
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