Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study
Obstructive sleep apnea (OSA) is associated with a broad range of frontal lobe dysfunctions. However, no study has investigated action monitoring, a crucial domain of frontal cognitive functions, in patients with OSA. By using the modified Flanker task, we tested the hypothesis that patients with OS...
Gespeichert in:
| Veröffentlicht in: | PloS one 2016-06, Vol.11 (6), p.e0157575-e0157575 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0157575 |
|---|---|
| container_issue | 6 |
| container_start_page | e0157575 |
| container_title | PloS one |
| container_volume | 11 |
| creator | Chou, Ping-Song Hsu, Chung-Yao Wu, Meng-Ni Liou, Li-Min Lu, Shinag-Ru Liu, Ching-Kuan Lai, Chiou-Lian |
| description | Obstructive sleep apnea (OSA) is associated with a broad range of frontal lobe dysfunctions. However, no study has investigated action monitoring, a crucial domain of frontal cognitive functions, in patients with OSA. By using the modified Flanker task, we tested the hypothesis that patients with OSA have an impaired action monitoring function. We recruited 25 untreated patients with moderate-severe OSA and 12 control participants who were matched for age, sex, apolipoprotein E4, and education level. Every enrolled participant underwent a standard overnight laboratory-based polysomnography and completed a modified Flanker task. Compared with the controls, the patients with OSA presented a significantly lower correct response rate in all trials (78.9% vs 95.9%, P = .008), congruent trials (84.7% vs 98.3%, P = .016), and incongruent trials (77.4% vs 94.7%, P = .009). The post-error correction rate was significantly lower in the patients with OSA than in the controls (74.9% vs 93.8%, P = .005). Furthermore, strong significant correlations were observed between the arousal index and correct rate in all trials (r = -0.390, P < .05) and in the incongruent trials (r = -0.429, P < .01), as well as between the arousal index and rate of post-error correction (r = -0.435, P < .01). We concluded that the action monitoring function was impaired in the patients with OSA. Sleep fragmentation was a major determinant of impaired action monitoring in these patients. |
| doi_str_mv | 10.1371/journal.pone.0157575 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_plos_</sourceid><recordid>TN_cdi_plos_journals_1796681931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_81a9423462744039ada60293f1a05ca9</doaj_id><sourcerecordid>4089240581</sourcerecordid><originalsourceid>FETCH-LOGICAL-c559t-9a7c182f0350da55dac8524e8db05a7bca4ad6d0af82264bd531d0dc47d214783</originalsourceid><addsrcrecordid>eNqFUttq3DAQNaWlubR_UFpDX_Lire6Xl8KSXhJISSHtsxhL8laLV9pKdmD_vt6sE5JSKHqQZnTmzJnhVNUbjBaYSvxhncYcoV9sU_QLhLmczrPqGGtKGkEQff7ofVSdlLJGiFMlxMvqiEg6BYgdVxdLO4QUm28phiHlEFf1p13pxniXrkOsr9sy5HEKb31903u_rZfb6KFu6mX9PfRpqG-G0e1eVS866It_Pd-n1c8vn3-cXzRX118vz5dXjeVcD40GabEiHaIcOeDcgVWcMK9cizjI1gIDJxyCThEiWOs4xQ45y6QjmElFT6t3B95tn4qZl1AMlloINQ2MJ8TlAeESrM02hw3knUkQzF0i5ZWBPATbe6MwaEYoE0QyhqgGBwIRTTsMiFvQE9fHudvYbryzPg4Z-iekT39i-GVW6dYwjSSTZCI4mwly-j36MphNKNb3PUSfxkm3QkqwSYH4P1RqyRnhai_r_V_Qfy-CHVA2p1Ky7x50Y2T2HrqvMnsPmdlDU9nbxzM_FN2bhv4BAOPDAw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1796681931</pqid></control><display><type>article</type><title>Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>Chou, Ping-Song ; Hsu, Chung-Yao ; Wu, Meng-Ni ; Liou, Li-Min ; Lu, Shinag-Ru ; Liu, Ching-Kuan ; Lai, Chiou-Lian</creator><creatorcontrib>Chou, Ping-Song ; Hsu, Chung-Yao ; Wu, Meng-Ni ; Liou, Li-Min ; Lu, Shinag-Ru ; Liu, Ching-Kuan ; Lai, Chiou-Lian</creatorcontrib><description>Obstructive sleep apnea (OSA) is associated with a broad range of frontal lobe dysfunctions. However, no study has investigated action monitoring, a crucial domain of frontal cognitive functions, in patients with OSA. By using the modified Flanker task, we tested the hypothesis that patients with OSA have an impaired action monitoring function. We recruited 25 untreated patients with moderate-severe OSA and 12 control participants who were matched for age, sex, apolipoprotein E4, and education level. Every enrolled participant underwent a standard overnight laboratory-based polysomnography and completed a modified Flanker task. Compared with the controls, the patients with OSA presented a significantly lower correct response rate in all trials (78.9% vs 95.9%, P = .008), congruent trials (84.7% vs 98.3%, P = .016), and incongruent trials (77.4% vs 94.7%, P = .009). The post-error correction rate was significantly lower in the patients with OSA than in the controls (74.9% vs 93.8%, P = .005). Furthermore, strong significant correlations were observed between the arousal index and correct rate in all trials (r = -0.390, P < .05) and in the incongruent trials (r = -0.429, P < .01), as well as between the arousal index and rate of post-error correction (r = -0.435, P < .01). We concluded that the action monitoring function was impaired in the patients with OSA. Sleep fragmentation was a major determinant of impaired action monitoring in these patients.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0157575</identifier><identifier>PMID: 27300504</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adult ; Alzheimer's disease ; Apnea ; Apolipoprotein E4 ; Arousal ; Biology and Life Sciences ; Case-Control Studies ; Clinical trials ; Cognitive ability ; Cross-Sectional Studies ; Error correction ; Family medical history ; Female ; Frontal lobe ; Frontal Lobe - physiopathology ; Hospitals ; Humans ; Hypoxia ; Male ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Monitoring ; Neural networks ; Neurology ; NMR ; Nuclear magnetic resonance ; Patients ; Physical Sciences ; Pilot Projects ; Polysomnography ; Sleep ; Sleep apnea ; Sleep Apnea, Obstructive - diagnosis ; Sleep Apnea, Obstructive - physiopathology ; Sleep deprivation ; Sleep disorders ; Social Sciences</subject><ispartof>PloS one, 2016-06, Vol.11 (6), p.e0157575-e0157575</ispartof><rights>2016 Chou et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2016 Chou et al 2016 Chou et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c559t-9a7c182f0350da55dac8524e8db05a7bca4ad6d0af82264bd531d0dc47d214783</citedby><cites>FETCH-LOGICAL-c559t-9a7c182f0350da55dac8524e8db05a7bca4ad6d0af82264bd531d0dc47d214783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907472/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907472/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27300504$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chou, Ping-Song</creatorcontrib><creatorcontrib>Hsu, Chung-Yao</creatorcontrib><creatorcontrib>Wu, Meng-Ni</creatorcontrib><creatorcontrib>Liou, Li-Min</creatorcontrib><creatorcontrib>Lu, Shinag-Ru</creatorcontrib><creatorcontrib>Liu, Ching-Kuan</creatorcontrib><creatorcontrib>Lai, Chiou-Lian</creatorcontrib><title>Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Obstructive sleep apnea (OSA) is associated with a broad range of frontal lobe dysfunctions. However, no study has investigated action monitoring, a crucial domain of frontal cognitive functions, in patients with OSA. By using the modified Flanker task, we tested the hypothesis that patients with OSA have an impaired action monitoring function. We recruited 25 untreated patients with moderate-severe OSA and 12 control participants who were matched for age, sex, apolipoprotein E4, and education level. Every enrolled participant underwent a standard overnight laboratory-based polysomnography and completed a modified Flanker task. Compared with the controls, the patients with OSA presented a significantly lower correct response rate in all trials (78.9% vs 95.9%, P = .008), congruent trials (84.7% vs 98.3%, P = .016), and incongruent trials (77.4% vs 94.7%, P = .009). The post-error correction rate was significantly lower in the patients with OSA than in the controls (74.9% vs 93.8%, P = .005). Furthermore, strong significant correlations were observed between the arousal index and correct rate in all trials (r = -0.390, P < .05) and in the incongruent trials (r = -0.429, P < .01), as well as between the arousal index and rate of post-error correction (r = -0.435, P < .01). We concluded that the action monitoring function was impaired in the patients with OSA. Sleep fragmentation was a major determinant of impaired action monitoring in these patients.</description><subject>Adult</subject><subject>Alzheimer's disease</subject><subject>Apnea</subject><subject>Apolipoprotein E4</subject><subject>Arousal</subject><subject>Biology and Life Sciences</subject><subject>Case-Control Studies</subject><subject>Clinical trials</subject><subject>Cognitive ability</subject><subject>Cross-Sectional Studies</subject><subject>Error correction</subject><subject>Family medical history</subject><subject>Female</subject><subject>Frontal lobe</subject><subject>Frontal Lobe - physiopathology</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Monitoring</subject><subject>Neural networks</subject><subject>Neurology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Patients</subject><subject>Physical Sciences</subject><subject>Pilot Projects</subject><subject>Polysomnography</subject><subject>Sleep</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - diagnosis</subject><subject>Sleep Apnea, Obstructive - physiopathology</subject><subject>Sleep deprivation</subject><subject>Sleep disorders</subject><subject>Social Sciences</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqFUttq3DAQNaWlubR_UFpDX_Lire6Xl8KSXhJISSHtsxhL8laLV9pKdmD_vt6sE5JSKHqQZnTmzJnhVNUbjBaYSvxhncYcoV9sU_QLhLmczrPqGGtKGkEQff7ofVSdlLJGiFMlxMvqiEg6BYgdVxdLO4QUm28phiHlEFf1p13pxniXrkOsr9sy5HEKb31903u_rZfb6KFu6mX9PfRpqG-G0e1eVS866It_Pd-n1c8vn3-cXzRX118vz5dXjeVcD40GabEiHaIcOeDcgVWcMK9cizjI1gIDJxyCThEiWOs4xQ45y6QjmElFT6t3B95tn4qZl1AMlloINQ2MJ8TlAeESrM02hw3knUkQzF0i5ZWBPATbe6MwaEYoE0QyhqgGBwIRTTsMiFvQE9fHudvYbryzPg4Z-iekT39i-GVW6dYwjSSTZCI4mwly-j36MphNKNb3PUSfxkm3QkqwSYH4P1RqyRnhai_r_V_Qfy-CHVA2p1Ky7x50Y2T2HrqvMnsPmdlDU9nbxzM_FN2bhv4BAOPDAw</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Chou, Ping-Song</creator><creator>Hsu, Chung-Yao</creator><creator>Wu, Meng-Ni</creator><creator>Liou, Li-Min</creator><creator>Lu, Shinag-Ru</creator><creator>Liu, Ching-Kuan</creator><creator>Lai, Chiou-Lian</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20160601</creationdate><title>Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study</title><author>Chou, Ping-Song ; Hsu, Chung-Yao ; Wu, Meng-Ni ; Liou, Li-Min ; Lu, Shinag-Ru ; Liu, Ching-Kuan ; Lai, Chiou-Lian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c559t-9a7c182f0350da55dac8524e8db05a7bca4ad6d0af82264bd531d0dc47d214783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Alzheimer's disease</topic><topic>Apnea</topic><topic>Apolipoprotein E4</topic><topic>Arousal</topic><topic>Biology and Life Sciences</topic><topic>Case-Control Studies</topic><topic>Clinical trials</topic><topic>Cognitive ability</topic><topic>Cross-Sectional Studies</topic><topic>Error correction</topic><topic>Family medical history</topic><topic>Female</topic><topic>Frontal lobe</topic><topic>Frontal Lobe - physiopathology</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypoxia</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Monitoring</topic><topic>Neural networks</topic><topic>Neurology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Patients</topic><topic>Physical Sciences</topic><topic>Pilot Projects</topic><topic>Polysomnography</topic><topic>Sleep</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - diagnosis</topic><topic>Sleep Apnea, Obstructive - physiopathology</topic><topic>Sleep deprivation</topic><topic>Sleep disorders</topic><topic>Social Sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chou, Ping-Song</creatorcontrib><creatorcontrib>Hsu, Chung-Yao</creatorcontrib><creatorcontrib>Wu, Meng-Ni</creatorcontrib><creatorcontrib>Liou, Li-Min</creatorcontrib><creatorcontrib>Lu, Shinag-Ru</creatorcontrib><creatorcontrib>Liu, Ching-Kuan</creatorcontrib><creatorcontrib>Lai, Chiou-Lian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chou, Ping-Song</au><au>Hsu, Chung-Yao</au><au>Wu, Meng-Ni</au><au>Liou, Li-Min</au><au>Lu, Shinag-Ru</au><au>Liu, Ching-Kuan</au><au>Lai, Chiou-Lian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>11</volume><issue>6</issue><spage>e0157575</spage><epage>e0157575</epage><pages>e0157575-e0157575</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Obstructive sleep apnea (OSA) is associated with a broad range of frontal lobe dysfunctions. However, no study has investigated action monitoring, a crucial domain of frontal cognitive functions, in patients with OSA. By using the modified Flanker task, we tested the hypothesis that patients with OSA have an impaired action monitoring function. We recruited 25 untreated patients with moderate-severe OSA and 12 control participants who were matched for age, sex, apolipoprotein E4, and education level. Every enrolled participant underwent a standard overnight laboratory-based polysomnography and completed a modified Flanker task. Compared with the controls, the patients with OSA presented a significantly lower correct response rate in all trials (78.9% vs 95.9%, P = .008), congruent trials (84.7% vs 98.3%, P = .016), and incongruent trials (77.4% vs 94.7%, P = .009). The post-error correction rate was significantly lower in the patients with OSA than in the controls (74.9% vs 93.8%, P = .005). Furthermore, strong significant correlations were observed between the arousal index and correct rate in all trials (r = -0.390, P < .05) and in the incongruent trials (r = -0.429, P < .01), as well as between the arousal index and rate of post-error correction (r = -0.435, P < .01). We concluded that the action monitoring function was impaired in the patients with OSA. Sleep fragmentation was a major determinant of impaired action monitoring in these patients.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>27300504</pmid><doi>10.1371/journal.pone.0157575</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2016-06, Vol.11 (6), p.e0157575-e0157575 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1796681931 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Adult Alzheimer's disease Apnea Apolipoprotein E4 Arousal Biology and Life Sciences Case-Control Studies Clinical trials Cognitive ability Cross-Sectional Studies Error correction Family medical history Female Frontal lobe Frontal Lobe - physiopathology Hospitals Humans Hypoxia Male Medicine Medicine and Health Sciences Middle Aged Monitoring Neural networks Neurology NMR Nuclear magnetic resonance Patients Physical Sciences Pilot Projects Polysomnography Sleep Sleep apnea Sleep Apnea, Obstructive - diagnosis Sleep Apnea, Obstructive - physiopathology Sleep deprivation Sleep disorders Social Sciences |
| title | Action-Monitoring Dysfunction in Obstructive Sleep Apnea - A Pilot Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T17%3A44%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Action-Monitoring%20Dysfunction%20in%20Obstructive%20Sleep%20Apnea%20-%20A%20Pilot%20Study&rft.jtitle=PloS%20one&rft.au=Chou,%20Ping-Song&rft.date=2016-06-01&rft.volume=11&rft.issue=6&rft.spage=e0157575&rft.epage=e0157575&rft.pages=e0157575-e0157575&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0157575&rft_dat=%3Cproquest_plos_%3E4089240581%3C/proquest_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1796681931&rft_id=info:pmid/27300504&rft_doaj_id=oai_doaj_org_article_81a9423462744039ada60293f1a05ca9&rfr_iscdi=true |