The Potential Impact of a Hepatitis C Vaccine for People Who Inject Drugs: Is a Vaccine Needed in the Age of Direct-Acting Antivirals?

The advent of highly effective hepatitis C (HCV) treatments has questioned the need for a vaccine to control HCV amongst people who inject drugs (PWID). However, high treatment costs and ongoing reinfection risk suggest it could still play a role. We compared the impact of HCV vaccination amongst PW...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0156213
Hauptverfasser:	Stone, Jack, Martin, Natasha K, Hickman, Matthew, Hellard, Margaret, Scott, Nick, McBryde, Emma, Drummer, Heidi, Vickerman, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral agents Antiviral Agents - therapeutic use Antiviral drugs Biology and Life Sciences Complications and side effects Cost analysis Disease transmission Drug abuse Drugs Effectiveness Epidemics Hepacivirus - drug effects Hepatitis Hepatitis B vaccines Hepatitis C Hepatitis C virus Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - epidemiology Hepatitis C, Chronic - prevention & control Heterogeneity Humans Incidence Infections Intravenous drug abuse Mathematical models Medicine Medicine and Health Sciences Models, Theoretical Parameter sensitivity People and Places Physiological aspects Prevalence Prevention Risk Risk factors Risk taking Substance abuse treatment Substance Abuse, Intravenous - epidemiology Time Factors Treatment Outcome United Kingdom - epidemiology Vaccination - methods Vaccines Viral Hepatitis Vaccines - economics Viral Hepatitis Vaccines - therapeutic use
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