Genetic Diversity, Natural Selection and Haplotype Grouping of Plasmodium knowlesi Gamma Protein Region II (PkγRII): Comparison with the Duffy Binding Protein (PkDBPαRII)

Plasmodium knowlesi is a simian malaria parasite that has been reported to cause malaria in humans in Southeast Asia. This parasite invades the erythrocytes of humans and of its natural host, the macaque Macaca fascicularis, via interaction between the Duffy binding protein region II (PkDBPαRII) and...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0155627-e0155627
Hauptverfasser:	Fong, Mun Yik, Rashdi, Sarah A A, Yusof, Ruhani, Lau, Yee Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Animals Antigens Antigens, Protozoan - genetics Binding proteins Biodiversity Biology and Life Sciences Borneo Causes of Cloning Cluster Analysis Clustering Comparative analysis Consent Deoxyribonucleic acid Differentiation DNA Duffy antigen Erythrocytes Erythrocytes - parasitology Ethics Gene sequencing Genetic analysis Genetic aspects Genetic diversity Genetic Variation Genetics, Population Geography Haplotypes Humans Infections Macaca fascicularis Malaria Malaysia Medical research Medicine Microscopy Mutation Natural selection Parasites Parasitology People and Places Phylogenetics Physiological aspects Plasmids Plasmodium (Protozoa) Plasmodium knowlesi Plasmodium knowlesi - genetics Polymerase chain reaction Polymorphism Polymorphism, Genetic Population genetics Proteins Protozoan Proteins - genetics Receptors, Cell Surface - genetics Research and Analysis Methods Selection, Genetic Sequence Analysis, DNA Statistical analysis Statistical methods Vector-borne diseases
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