A Conserved Epitope Mapped with a Monoclonal Antibody against the VP3 Protein of Goose Parvovirus by Using Peptide Screening and Phage Display Approaches

Waterfowl parvovirus (WPV) infection causes high mortality and morbidity in both geese (Anser anser) and Muscovy ducks (Cairina moschata), resulting in significant losses to the waterfowl industries. The VP3 protein of WPV is a major structural protein that induces neutralizing antibodies in the wat...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0147361-e0147361
Hauptverfasser:	Li, Chenxi, Liu, Hongyu, Li, Jinzhe, Liu, Dafei, Meng, Runze, Zhang, Qingshan, Shaozhou, Wulin, Bai, Xiaofei, Zhang, Tingting, Liu, Ming, Zhang, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animals Anser anser Antibodies, Monoclonal - immunology Antibodies, Neutralizing - immunology Antibodies, Viral - immunology Antigenic determinants Antigens Aquatic birds Binding Biology and Life Sciences Biotechnology Cairina moschata Capsid Proteins - immunology Cells, Cultured Conserved sequence Diseases and pests Ducks - virology Enzyme-linked immunosorbent assay Epitope Mapping - methods Epitopes Epitopes, B-Lymphocyte - immunology Ethics Geese Geese - virology Genetic aspects Goose parvovirus Health aspects Immunoglobulins Laboratory animals Lymphocytes B Medical screening Monoclonal antibodies Morbidity Neutralizing Parvoviridae Parvoviridae Infections - prevention & control Parvoviridae Infections - veterinary Parvoviridae Infections - virology Parvovirus Parvovirus - immunology Parvoviruses Peptide Library Peptides Phage display Phages Physiological aspects Proteins Research and Analysis Methods Residues Sequence Analysis, Protein Topology Virology Viruses VP3 protein Waterfowl Western blotting
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