Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

The simian immunodeficiency virus (SIV) challenge model of lentiviral infection is often used as a model to human immunodeficiency virus type 1 (HIV-1) for studying vaccine mediated and immune correlates of protection. However, knowledge of the structure of the SIV envelope (Env) glycoprotein is lim...

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Veröffentlicht in:	PLoS pathogens 2016-04, Vol.12 (4), p.e1005537-e1005537
Hauptverfasser:	Mason, Rosemarie D, Welles, Hugh C, Adams, Cameron, Chakrabarti, Bimal K, Gorman, Jason, Zhou, Tongqing, Nguyen, Richard, O'Dell, Sijy, Lusvarghi, Sabrina, Bewley, Carole A, Li, Hui, Shaw, George M, Sheng, Zizhang, Shapiro, Lawrence, Wyatt, Richard, Kwong, Peter D, Mascola, John R, Roederer, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS vaccines Amino Acid Sequence Amino acids Analysis Animals Antibodies, Monoclonal - immunology Antibodies, Neutralizing - immunology Antigenic determinants B cells Binding Sites Biology and Life Sciences Clinical trials Development and progression Epitopes - immunology Gene Products, env - immunology Health aspects HIV HIV Antibodies - immunology HIV Antibodies - isolation & purification Human immunodeficiency virus Human immunodeficiency virus 1 Humans Immunization Immunoglobulins Immunotherapy Infection Infections Medicine and Health Sciences Monoclonal antibodies Neutralization Tests - methods Primates Proteins Research and Analysis Methods Simian immunodeficiency virus Simian Immunodeficiency Virus - immunology Swine influenza virus Vaccines
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