The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial

Malaria transmission is highly heterogeneous, generating malaria hotspots that can fuel malaria transmission across a wider area. Targeting hotspots may represent an efficacious strategy for reducing malaria transmission. We determined the impact of interventions targeted to serologically defined ma...

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Veröffentlicht in:	PLoS medicine 2016-04, Vol.13 (4), p.e1001993
Hauptverfasser:	Bousema, Teun, Stresman, Gillian, Baidjoe, Amrish Y, Bradley, John, Knight, Philip, Stone, William, Osoti, Victor, Makori, Euniah, Owaga, Chrispin, Odongo, Wycliffe, China, Pauline, Shagari, Shehu, Doumbo, Ogobara K, Sauerwein, Robert W, Kariuki, Simon, Drakeley, Chris, Stevenson, Jennifer, Cox, Jonathan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Anopheles Antibodies, Protozoan - blood Biology and Life Sciences Blood Child Child, Preschool Clinical trials Confidence intervals Culicidae - growth & development Culicidae - parasitology Disease Reservoirs Disease transmission DNA, Protozoan - blood DNA, Protozoan - genetics Female Health aspects Host-Parasite Interactions Humans Incidence Insect Vectors - growth & development Insect Vectors - parasitology Insecticide-Treated Bednets Insecticides Intervention Kenya - epidemiology Land settlement Malaria Malaria - diagnosis Malaria - epidemiology Malaria - parasitology Malaria - prevention & control Malaria - transmission Male Medical research Medicine and Health Sciences Mosquito Control - methods Mosquitoes Parasites Parasitic diseases Physical Sciences Plasmodium - genetics Plasmodium - growth & development Plasmodium - immunology Polymerase Chain Reaction Population Density Prevalence Research and Analysis Methods Researchers Risk factors Rural Health Services Seroepidemiologic Studies Studies Time Factors Young Adult
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