MicroRNA Profile in CD8+ T-Lymphocytes from HIV-Infected Individuals: Relationship with Antiviral Immune Response and Disease Progression

The relationship between host microRNAs (miRNA), viral control and immune response has not yet been elucidated in the field of HIV. The aim of this study was to assess the differential miRNA profile in CD8+ T-cells between HIV-infected individuals who differ in terms of viral replication control and...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0155245-e0155245
Hauptverfasser:	Egaña-Gorroño, Lander, Guardo, Alberto C, Bargalló, Manel E, Planet, Evarist, Vilaplana, Elisenda, Escribà, Tuixent, Pérez, Iñaki, Gatell, Josep Maria, García, Felipe, Arnedo, Mireia, Plana M, Montserrat
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Algorithms Analysis Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Antiretroviral drugs Antiviral drugs Apoptosis Biology and life sciences Care and treatment CD28 antigen CD3 antigen CD8 antigen CD8-Positive T-Lymphocytes - immunology Cellular signal transduction Complications and side effects Control methods Controllers Disease control Disease Progression Enrichment Female Gene expression Gene Expression Profiling Genes HIV HIV infections HIV Infections - drug therapy HIV Infections - genetics HIV Infections - immunology HIV Infections - pathology Human immunodeficiency virus Humans Immune response Immune response (cell-mediated) Immune system Immunity - drug effects Influence Lymphocytes Lymphocytes T Male Medicine and Health Sciences MicroRNA MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miRNA Real-Time Polymerase Chain Reaction Reproducibility of Results Ribonucleic acid RNA T cell receptors Transduction Virus replication
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