Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models

We aimed to evaluate the value of immunohistochemical markers and serum CA125 in predicting the risk of lymph node metastasis (LNM) in women with endometrial cancer and to identify a low-risk group of LNM. The medical records of 370 patients with endometrial endometrioid adenocarcinoma who underwent...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0155145-e0155145
Hauptverfasser:	Yang, Bingyi, Shan, Boer, Xue, Xiaohong, Wang, Huaying, Shan, Weiwei, Ning, Chengcheng, Zhou, Qiongjie, Chen, Xiaojun, Luo, Xuezhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adult Aged Analysis Area Under Curve Biology and Life Sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biopsy CA-125 Antigen - blood CA-125 Antigen - genetics Cancer Cancer metastasis Carcinoma, Endometrioid - diagnosis Carcinoma, Endometrioid - genetics Carcinoma, Endometrioid - pathology Carcinoma, Endometrioid - surgery Cloning Development and progression Endometrial cancer Endometrial Neoplasms - diagnosis Endometrial Neoplasms - genetics Endometrial Neoplasms - pathology Endometrial Neoplasms - surgery Endometrium Female Gynecology Health aspects Health risks Hospitals Humans Immunohistochemistry Ki-67 Antigen - genetics Ki-67 Antigen - metabolism Laboratories Lymph Lymph nodes Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis Lymphatic system Markers Mathematical models Medical prognosis Medical records Medicine and Health Sciences Membrane Proteins - blood Membrane Proteins - genetics Metastases Metastasis Middle Aged NMR Nuclear magnetic resonance Obstetrics Patients Physical Sciences Prediction models Predictive Value of Tests Progesterone Prognosis Receptors, Progesterone - genetics Receptors, Progesterone - metabolism Research and Analysis Methods Retrospective Studies Risk Risk Assessment Risk groups Surgery Uterine cancer
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