Influence of a Double-Lumen Extension Tube on Drug Delivery: Examples of Isosorbide Dinitrate and Diazepam

Plastic materials such as polyurethane (PUR), polyethylene (PE), polypropylene (PP) and polyvinyl chloride (PVC) are widely used in double-lumen extension tubing. The purposes of our study were to 1) compare in vitro drug delivery through the double extension tubes available on the market 2) assess...

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Veröffentlicht in:	PloS one 2016-05, Vol.11 (5), p.e0154917-e0154917
Hauptverfasser:	Maiguy-Foinard, Aurélie, Blanchemain, Nicolas, Barthélémy, Christine, Décaudin, Bertrand, Odou, Pascal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Biomedical materials Comparative analysis Diazepam Diazepam - administration & dosage Diazepam - analysis Dosage and administration Drug delivery Drug delivery systems Drug Delivery Systems - instrumentation Drugs Egress Extrusion Feasibility studies Food additives Humans Infusions, Intravenous - instrumentation Innovations Intensive care Isosorbide dinitrate Isosorbide Dinitrate - administration & dosage Isosorbide Dinitrate - analysis Life Sciences Limit of Detection Medical equipment Medical tubing Medicine and Health Sciences Migration Norepinephrine Pharmaceutical sciences Pharmacy Physical Sciences Plastic properties Plastics Polyethylene Polyethylenes Polymers Polypropylene Polyurethane Polyurethane resins Polyvinyl chloride Reference materials Sorption Spectrophotometry Spectrophotometry, Ultraviolet Sterilization Syringes Tubes
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