A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom

Envenoming by coral snakes (Elapidae: Micrurus), although not abundant, represent a serious health threat in the Americas, especially because antivenoms are scarce. The development of adequate amounts of antielapidic serum for the treatment of accidents caused by snakes like Micrurus corallinus is a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS neglected tropical diseases 2016-03, Vol.10 (3), p.e0004484-e0004484
Hauptverfasser:	Ramos, Henrique Roman, Junqueira-de-Azevedo, Inácio de Loiola M, Novo, Juliana Branco, Castro, Karen, Duarte, Clara Guerra, Machado-de-Ávila, Ricardo A, Chavez-Olortegui, Carlos, Ho, Paulo Lee
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antigens Antivenins - immunology Antivenins - pharmacology Biology and Life Sciences Coral snakes Deoxyribonucleic acid Development and progression Development strategies Disease Models, Animal DNA Elapidae - genetics Elapidae - immunology Epitopes, B-Lymphocyte - genetics Epitopes, B-Lymphocyte - immunology Female Genes Health aspects Health risks Immune serums Immunization Immunoglobulins Medicine and Health Sciences Mice, Inbred BALB C Micrurus Mortality Neutralization Tests Physical Sciences Physiological aspects Proteins Snake bites Snake Bites - therapy Snake Venoms - genetics Snake Venoms - immunology Snakes Technology, Pharmaceutical - methods Toxins Tropical diseases Vaccination - methods Vaccines, DNA - administration & dosage Vaccines, DNA - immunology Vaccines, Subunit - administration & dosage Vaccines, Subunit - immunology Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Venom Ventilation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!