Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies
Today, the World Health Organization recognizes 17 major parasitic and related infections as the neglected tropical diseases (NTDs). Despite recent gains in the understanding of the nature and prevalence of NTDs, as well as successes in recent scaled-up preventive chemotherapy strategies and other h...
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description | Today, the World Health Organization recognizes 17 major parasitic and related infections as the neglected tropical diseases (NTDs). Despite recent gains in the understanding of the nature and prevalence of NTDs, as well as successes in recent scaled-up preventive chemotherapy strategies and other health interventions, the NTDs continue to rank among the world's greatest global health problems. For virtually all of the NTDs (including those slated for elimination under the auspices of a 2012 London Declaration for NTDs and a 2013 World Health Assembly resolution [WHA 66.12]), additional control mechanisms and tools are needed, including new NTD drugs, vaccines, diagnostics, and vector control agents and strategies. Elimination will not be possible without these new tools. Here we summarize some of the key challenges in translational science to develop and introduce these new technologies in order to ensure success in global NTD elimination efforts. |
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Despite recent gains in the understanding of the nature and prevalence of NTDs, as well as successes in recent scaled-up preventive chemotherapy strategies and other health interventions, the NTDs continue to rank among the world's greatest global health problems. For virtually all of the NTDs (including those slated for elimination under the auspices of a 2012 London Declaration for NTDs and a 2013 World Health Assembly resolution [WHA 66.12]), additional control mechanisms and tools are needed, including new NTD drugs, vaccines, diagnostics, and vector control agents and strategies. Elimination will not be possible without these new tools. 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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, et al. (2016) Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. PLoS Negl Trop Dis 10(3): e0003895. doi:10.1371/journal.pntd.0003895</rights><rights>2016 Hotez et al 2016 Hotez et al</rights><rights>2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, et al. (2016) Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. 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subjects | Animals Biology and Life Sciences Care and treatment Chemotherapy Communicable Disease Control - methods Communicable Diseases - epidemiology Disease Eradication Disease prevention Drugs Funding Health aspects Humans Infections Medicine and Health Sciences Neglected Diseases - epidemiology Parasitic diseases Pharmaceutical industry R&D Research & development Review Science Studies Translational Research, Biomedical Tropical Climate Tropical diseases Vaccines |
title | Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies |
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