Cerebral Metabolic Differences Associated with Cognitive Impairment in Parkinson's Disease

To characterize cerebral glucose metabolism associated with different cognitive states in Parkinson's disease (PD) using 18F-fluorodeoxyglucose (FDG) and Positron Emission Tomography (PET). Three groups of patients were recruited in this study including PD patients with dementia (PDD; n = 10),...

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Veröffentlicht in:	PloS one 2016-04, Vol.11 (4), p.e0152716-e0152716
Hauptverfasser:	Tang, Yilin, Ge, Jingjie, Liu, Fengtao, Wu, Ping, Guo, Sisi, Liu, Zhenyang, Wang, Yixuan, Wang, Ying, Ding, Zhengtong, Wu, Jianjun, Zuo, Chuantao, Wang, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Biology and Life Sciences Brain - metabolism Brain - physiopathology Cerebral Cortex - metabolism Cerebral Cortex - physiopathology Cognition Cognition & reasoning Cognitive ability Cognitive Dysfunction - etiology Cognitive Dysfunction - metabolism Cortex Dementia Dementia - etiology Dementia - metabolism Dementia disorders Dopamine Female Fluorodeoxyglucose F18 Glucose metabolism Humans Hypometabolism Impairment Levodopa Levodopa - metabolism Male Medicine and Health Sciences Mental depression Metabolism Metabolites Middle Aged Movement disorders Neurodegenerative diseases Neurology Neuropsychological Tests Nuclear medicine Occipital lobes Parahippocampal gyrus Parkinson disease Parkinson Disease - complications Parkinson Disease - metabolism Parkinson's disease Patients Positron emission Positron emission tomography Positron-Emission Tomography - methods Research and Analysis Methods Risk factors Social Sciences Studies Tomography
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