Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements

Measurements of glycolytic rate and maximum glycolytic capacity using extracellular flux analysis can give crucial information about cell status and phenotype during normal operation, development of pathology, differentiation, and malignant transformation. They are also of great use when assessing t...

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Veröffentlicht in:	PloS one 2016-03, Vol.11 (3), p.e0152016-e0152016
Hauptverfasser:	Mookerjee, Shona A, Nicholls, David G, Brand, Martin D
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidification Adenosine Triphosphate - metabolism Adherent cells Aging Animals Biochemistry - methods Bioenergetics Biology and Life Sciences Cancer Cell culture Cell Line Cell metabolism Cell Respiration Fibroblasts - metabolism Fluctuations Flux Genetic transformation Glycolysis Heart failure HEK293 Cells Humans Hyperoxia Metabolism Mice Myoblasts - metabolism Oxidative Phosphorylation Pharmacy Phosphorylation Physical Sciences Physiological aspects Respiration Sodium-Potassium-Exchanging ATPase - metabolism Stem cells Transformation
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