Insulin Resistance in PCOS Patients Enhances Oxidative Stress and Leukocyte Adhesion: Role of Myeloperoxidase

Cardiovascular diseases and oxidative stress are related to polycystic ovary syndrome (PCOS) and insulin resistance (IR). We have evaluated the relationship between myeloperoxidase (MPO) and leukocyte activation in PCOS patients according to homeostatic model assessment of IR (HOMA-IR), and have exp...

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Veröffentlicht in:	PloS one 2016-03, Vol.11 (3), p.e0151960-e0151960
Hauptverfasser:	Victor, Victor M, Rovira-Llopis, Susana, Bañuls, Celia, Diaz-Morales, Noelia, Martinez de Marañon, Arantxa, Rios-Navarro, Cesar, Alvarez, Angeles, Gomez, Marcelino, Rocha, Milagros, Hernández-Mijares, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adult Age Analysis Anthropometry Atherosclerosis Biology and Life Sciences Biomedical research Cardiovascular disease Cardiovascular diseases Cell activation Cell Adhesion Cell adhesion molecules Cytokines Cytokines - metabolism Diabetes Diagnosis E-selectin Endocrinology Endothelial cells Endothelium Female Health care facilities Heart diseases Hospitals Humans Inflammation Inflammation Mediators - metabolism Insulin Insulin Resistance Intercellular adhesion molecule 1 Interleukin 6 Kinases Leukocyte rolling Leukocytes Leukocytes - cytology Medical research Medicine and Health Sciences Metabolic syndrome Mitochondria Mitochondria - metabolism Oxidation resistance Oxidative Stress Oxygen Patients Peroxidase Peroxidase - metabolism Pharmacology Physiological aspects Physiology Polycystic ovary syndrome Polycystic Ovary Syndrome - metabolism Polycystic Ovary Syndrome - pathology Polycystic Ovary Syndrome - physiopathology Population studies Reactive oxygen species Reactive Oxygen Species - metabolism Research and Analysis Methods Risk factors Tumor necrosis factor-α Umbilical vein Vascular cell adhesion molecule 1 White blood cells Womens health Young Adult
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