Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences

Simian-human immunodeficiency virus (SHIV) challenge stocks are critical for preclinical testing of vaccines, antibodies, and other interventions aimed to prevent HIV-1. A major unmet need for the field has been the lack of a SHIV challenge stock expressing circulating recombinant form 01_AE (CRF01_...

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Veröffentlicht in:	PLoS pathogens 2016-02, Vol.12 (2), p.e1005431-e1005431
Hauptverfasser:	Tartaglia, Lawrence J, Chang, Hui-Wen, Lee, Benjamin C, Abbink, Peter, Ng'ang'a, David, Boyd, Michael, Lavine, Christy L, Lim, So-Yon, Sanisetty, Srisowmya, Whitney, James B, Seaman, Michael S, Rolland, Morgane, Tovanabutra, Sodsai, Ananworanich, Jintanat, Robb, Merlin L, Kim, Jerome H, Michael, Nelson L, Barouch, Dan H
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Vaccines - immunology Animals Antibodies, Neutralizing - immunology Biology and Life Sciences Cells, Cultured Female HIV HIV Antibodies - immunology HIV infections HIV-1 - immunology Human immunodeficiency virus Humans Innovations Macaca mulatta Male Medicine and Health Sciences Mutation Prevention Recombinant molecules Research and Analysis Methods Simian Acquired Immunodeficiency Syndrome - immunology Simian Immunodeficiency Virus - genetics Studies Viral vaccines Viremia - immunology Viruses
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