SiteOut: An Online Tool to Design Binding Site-Free DNA Sequences

DNA-binding proteins control many fundamental biological processes such as transcription, recombination and replication. A major goal is to decipher the role that DNA sequence plays in orchestrating the binding and activity of such regulatory proteins. To address this goal, it is useful to rationall...

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Veröffentlicht in:	PloS one 2016-03, Vol.11 (3), p.e0151740-e0151740
Hauptverfasser:	Estrada, Javier, Ruiz-Herrero, Teresa, Scholes, Clarissa, Wunderlich, Zeba, DePace, Angela H
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Base Sequence Binding sites Binding Sites - genetics Biological activity Biology Biology and Life Sciences Chemical properties Deoxyribonucleic acid Design DNA DNA - genetics DNA biosynthesis DNA sequencing DNA-binding protein DNA-Binding Proteins - genetics Drosophila Experiments Gene expression Gene sequencing Genetics Influence Insects Internet Medical research Medical schools Nucleotide sequence Physical Sciences Protein Binding - genetics Proteins Recombination Regulatory proteins Regulatory sequences Research and Analysis Methods Sequence Analysis, DNA Software Transcription Transcription factors Transcription, Genetic
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