Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction

In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug di...

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Veröffentlicht in:PLoS computational biology 2016-02, Vol.12 (2), p.e1004760-e1004760
Hauptverfasser: Liu, Yong, Wu, Min, Miao, Chunyan, Zhao, Peilin, Li, Xiao-Li
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Sprache:eng
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