Transient Pinning and Pulling: A Mechanism for Bending Microtubules

Microtubules have a persistence length of the order of millimeters in vitro, but inside cells they bend over length scales of microns. It has been proposed that polymerization forces bend microtubules in the vicinity of the cell boundary or other obstacles, yet bends develop even when microtubules a...

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Veröffentlicht in:	PloS one 2016-03, Vol.11 (3), p.e0151322-e0151322
Hauptverfasser:	Kent, Ian A, Rane, Parag S, Dickinson, Richard B, Ladd, Anthony J C, Lele, Tanmay P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bends Biological Transport Biology and Life Sciences Biomechanical Phenomena Cell cycle Cell Nucleus - metabolism Chemical engineering Computer Simulation Dynein Dyneins - metabolism Epithelial cells LLC-PK1 Cells Microtubules Microtubules - metabolism Models, Biological Motility Myosin Myosins - metabolism Photobleaching Physical Sciences Physiological aspects Polymerization Properties Rotation Swine Transport
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