Impact of Aldosterone Antagonists on Sudden Cardiac Death Prevention in Heart Failure and Post-Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Sudden cardiac death (SCD) is a severe burden of modern medicine. Aldosterone antagonist is publicized as effective in reducing mortality in patients with heart failure (HF) or post myocardial infarction (MI). Our study aimed to assess the efficacy of AAs on mortality including SCD, hospitalization...

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Veröffentlicht in:	PloS one 2016-02, Vol.11 (2), p.e0145958-e0145958
Hauptverfasser:	Le, Hai-Ha, El-Khatib, Chadia, Mombled, Margaux, Guitarian, Frédéric, Al-Gobari, Muaamar, Fall, Mor, Janiaud, Perrine, Marchant, Ivanny, Cucherat, Michel, Bejan-Angoulvant, Théodora, Gueyffier, François
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone Analysis Antagonists Beta blockers Biology and Life Sciences Cardiac arrhythmia Cardiovascular diseases Care and treatment Clinical trials Death Death, Sudden, Cardiac - pathology Death, Sudden, Cardiac - prevention & control Dosage and administration Drugs Glucocorticoids Gynecomastia Gynecomastia - etiology Gynecomastia - pathology Health aspects Heart Heart attack Heart diseases Heart Failure - mortality Heart Failure - pathology Heart Failure - prevention & control Humans Hyperkalemia Hyperkalemia - etiology Hyperkalemia - pathology Libraries Life Sciences Medical ethics Medicine and Health Sciences Meta-analysis Mineralocorticoid Receptor Antagonists - administration & dosage Mineralocorticoid Receptor Antagonists - adverse effects Mortality Myocardial infarction Myocardial Infarction - mortality Myocardial Infarction - pathology Myocardial Infarction - prevention & control Odds Ratio Patient outcomes Patients People and Places Physical Sciences Prevention Prospective Studies Randomization Randomized Controlled Trials as Topic Renal function Renal Insufficiency - etiology Renal Insufficiency - pathology Research and Analysis Methods Risk assessment Side effects Studies Subgroups Survival Analysis Treatment Outcome United States
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