Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting. We performed a two-stage GWAS analysis of incident myocardial infarcti...

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Veröffentlicht in:	PloS one 2016-03, Vol.11 (3), p.e0144997-e0144997
Hauptverfasser:	Dehghan, Abbas, Bis, Joshua C, White, Charles C, Smith, Albert Vernon, Morrison, Alanna C, Cupples, L Adrienne, Trompet, Stella, Chasman, Daniel I, Lumley, Thomas, Völker, Uwe, Buckley, Brendan M, Ding, Jingzhong, Jensen, Majken K, Folsom, Aaron R, Kritchevsky, Stephen B, Girman, Cynthia J, Ford, Ian, Dörr, Marcus, Salomaa, Veikko, Uitterlinden, André G, Eiriksdottir, Gudny, Vasan, Ramachandran S, Franceschini, Nora, Carty, Cara L, Virtamo, Jarmo, Demissie, Serkalem, Amouyel, Philippe, Arveiler, Dominique, Heckbert, Susan R, Ferrières, Jean, Ducimetière, Pierre, Smith, Nicholas L, Wang, Ying A, Siscovick, David S, Rice, Kenneth M, Wiklund, Per-Gunnar, Taylor, Kent D, Evans, Alun, Kee, Frank, Rotter, Jerome I, Karvanen, Juha, Kuulasmaa, Kari, Heiss, Gerardo, Kraft, Peter, Launer, Lenore J, Hofman, Albert, Markus, Marcello R P, Rose, Lynda M, Silander, Kaisa, Wagner, Peter, Benjamin, Emelia J, Lohman, Kurt, Stott, David J, Rivadeneira, Fernando, Harris, Tamara B, Levy, Daniel, Liu, Yongmei, Rimm, Eric B, Jukema, J Wouter, Völzke, Henry, Ridker, Paul M, Blankenberg, Stefan, Franco, Oscar H, Gudnason, Vilmundur, Psaty, Bruce M, Boerwinkle, Eric, O'Donnell, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Biology and Life Sciences Biomedical research Cardiology Cardiovascular disease Cardiovascular diseases Chromosomes Cohort analysis Cohort Studies Consortia Cooperative Behavior Coronary artery disease Coronary Artery Disease - epidemiology Coronary Artery Disease - genetics Coronary heart disease Coronary vessels Disease control Epidemiology Female Gene expression Genetic aspects Genetic diversity Genetic polymorphisms Genetic Predisposition to Disease Genetic variance Genetics Genome-wide association studies Genome-Wide Association Study Genomes Genomics Geriatrics Health aspects Health care Heart attack Heart attacks Heart diseases Hospitals Humans Internal medicine Loci Male Medical prognosis Medical research Medicine and Health Sciences Meta-analysis Middle Aged Mortality Myocardial infarction Myocardial Infarction - epidemiology Myocardial Infarction - genetics Physical Sciences Physiological aspects Polymorphism, Single Nucleotide Preventive medicine Prognosis Prospective Studies Public health R&D Research & development Research and Analysis Methods Risk Risk factors Science Single-nucleotide polymorphism Systematic review
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