Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis

To discover novel prognostic biomarkers in ovarian serous carcinomas. A meta-analysis of all single genes probes in the TCGA and HAS ovarian cohorts was performed to identify possible biomarkers using Cox regression as a continuous variable for overall survival. Genes were ranked by p-value using St...

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Veröffentlicht in:	PloS one 2016-02, Vol.11 (2), p.e0149183-e0149183
Hauptverfasser:	Willis, Scooter, Villalobos, Victor M, Gevaert, Olivier, Abramovitz, Mark, Williams, Casey, Sikic, Branimir I, Leyland-Jones, Brian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous polyposis coli Antagonists Aquaporin 1 Axl protein Bioinformatics Biological markers Biology and Life Sciences Biomarkers Biomarkers, Tumor - genetics Cancer Care and treatment Chemotherapy Complications and side effects Continuity (mathematics) E-cadherin False Positive Reactions Female Gene expression Gene Expression Regulation, Neoplastic Genes Genes, Neoplasm Genetic aspects Genetic Predisposition to Disease Health aspects Humans Kinases Medicine Medicine and Health Sciences Meta-analysis Metadata Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - genetics People and Places Physical Sciences PTEN-induced putative kinase Regression analysis Regulators Research and Analysis Methods Statistical analysis Survival analysis
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