Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export

The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC). Here we show that Dbp5 is also required for the nuclear export of both pre-ribosomal subunits. Y...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2016-02, Vol.11 (2), p.e0149571-e0149571
Hauptverfasser:	Neumann, Bettina, Wu, Haijia, Hackmann, Alexandra, Krebber, Heike
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Adenosine triphosphatase Baking yeast Biology and life sciences Biosynthesis Cytoplasm DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism DNA helicase Exports Genetic aspects Helicases Messenger RNA mRNA Mutants Mutation Nuclear Pore Complex Proteins - metabolism Nuclear Proteins - metabolism Nuclear transport Nucleocytoplasmic Transport Proteins - genetics Nucleocytoplasmic Transport Proteins - metabolism Physiological aspects Plasmids Protein Binding Proteins Research and Analysis Methods Ribonucleic acid Ribosomal subunits Ribosome Subunits - metabolism Ribosomes RNA RNA helicase RNA Transport RNA, Fungal - metabolism RNA-Binding Proteins - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Temperature requirements Transport Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!