Dietary Fiber Intake Regulates Intestinal Microflora and Inhibits Ovalbumin-Induced Allergic Airway Inflammation in a Mouse Model

Recently, academic studies suggest that global growth of airway allergic disease has a close association with dietary changes including reduced consumption of fiber. Therefore, appropriate dietary fiber supplementation might be potential to prevent airway allergic disease (AAD). We investigated whet...

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Veröffentlicht in:	PloS one 2016-02, Vol.11 (2), p.e0147778-e0147778
Hauptverfasser:	Zhang, Zhiyu, Shi, Lei, Pang, Wenhui, Liu, Wenwen, Li, Jianfeng, Wang, Haibo, Shi, Guanggang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma Bacteria Bacteroidetes - drug effects Bacteroidetes - growth & development Bifidobacterium - drug effects Bifidobacterium - growth & development Biology and Life Sciences Body weight Cellulose Cellulose - administration & dosage Control methods Cytokines Deoxyribonucleic acid Diet Dietary fiber Dietary Fiber - therapeutic use Dietary intake Dietary supplements Disease Models, Animal Disease prevention DNA E coli Enzyme-linked immunosorbent assay Eosinophils - drug effects Eosinophils - immunology Escherichia coli Feces - microbiology Female Food allergies Gastrointestinal Microbiome - drug effects Gastrointestinal Microbiome - immunology Goblet Cells - drug effects Goblet Cells - immunology Humans Hypersensitivity Immunity Immunoglobulin E Immunoglobulin E - biosynthesis Infiltration Inflammation Inflammatory response Interferon Intestinal microflora Intestine Intestines - drug effects Intestines - immunology Intestines - microbiology Laboratories Lactobacillus - drug effects Lactobacillus - growth & development Leukocytes (eosinophilic) Lung - drug effects Lung - immunology Lungs Lymphocytes T Medicine and Health Sciences Metaplasia Mice Mice, Inbred BALB C Mucosa Nasal Mucosa - drug effects Nasal Mucosa - immunology Otolaryngology Otology Ovalbumin Pectin Pectins - administration & dosage Physical Sciences Prebiotics Probiotics Proteobacteria - drug effects Proteobacteria - growth & development Qualitative analysis Research and Analysis Methods Respiratory Hypersensitivity - chemically induced Respiratory Hypersensitivity - diet therapy Respiratory Hypersensitivity - immunology Respiratory Hypersensitivity - microbiology Respiratory tract Respiratory tract diseases RNA, Ribosomal, 16S - genetics Rubbing Sneezing Surgery Th1-Th2 Balance - drug effects γ-Interferon
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