A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases

Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing chemical information from high throughput screenings is changing the landscape of drug discovery for these diseases. In this work we took advantag...

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Veröffentlicht in:	PLoS neglected tropical diseases 2016-01, Vol.10 (1), p.e0004300-e0004300
Hauptverfasser:	Berenstein, Ariel José, Magariños, María Paula, Chernomoretz, Ariel, Agüero, Fernán
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiparasitic Agents - isolation & purification Biological activity Computational Biology - methods Cost control Drug Discovery - methods Drug Repositioning - methods Drug targeting Drug therapy Drugs E coli Experiments Humans Innovations Methods Mice Neglected Diseases - drug therapy Organisms Pathogens Pharmaceutical industry Proteins Public health administration R&D Research & development Tropical diseases
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