Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1

Replication forks are vulnerable to wayward nuclease activities. We report here our discovery of a new member in guarding genome stability at replication forks. We previously isolated a Drosophila mutation, wuho (wh, no progeny), characterized by a severe fertility defect and affecting expression of...

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Veröffentlicht in:PLoS biology 2016-01, Vol.14 (1), p.e1002349-e1002349
Hauptverfasser: Cheng, I-Cheng, Chen, Betty Chamay, Shuai, Hung-Hsun, Chien, Fan-Ching, Chen, Peilin, Hsieh, Tao-shih
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Sprache:eng
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