Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation

Lung transplantation exposes the donated lung to a period of anoxia. Re-establishing the circulation after ischemia stimulates inflammation causing organ damage. Since our published data established that activin A is a key pro-inflammatory cytokine, we assessed the roles of activin A and B, and thei...

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Veröffentlicht in:	PloS one 2016-01, Vol.11 (1), p.e0140948-e0140948
Hauptverfasser:	de Kretser, David M, Bensley, Jonathan G, Phillips, David J, Levvey, Bronwyn J, Snell, Greg I, Lin, Enjarn, Hedger, Mark P, O'Hehir, Robyn E
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Activins Activins - blood Adult Amino acids Anesthesia Anoxia Anticoagulants Binding proteins Biology and Life Sciences Coagulants Conditioning Cystic fibrosis Cytokines Cytokines - blood Developmental biology Endocrinology Ethics Female Follistatin Follistatin - blood Genetic aspects Heparin Hepatology Hospitals Humans Immunology Inflammation Ischemia Ischemic Preconditioning Lung Diseases, Obstructive - blood Lung Diseases, Obstructive - surgery Lung transplantation Lung Transplantation - methods Male Medical research Medicine Medicine and Health Sciences Methods Middle Aged Patients Physiological aspects Proteins Randomized Controlled Trials as Topic Reperfusion Surgery Transplantation Transplants & implants Treatment Outcome
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