Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs

The role of vascular endothelial growth factor (VEGF)-induced 3 different nitric oxide synthase (NOS) isoforms in lung development and injury in the newborn (NB) lung are not known. We hypothesized that VEGF-induced specific NOS pathways are critical regulators of lung development and injury. We stu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2016-01, Vol.11 (1), p.e0147588-e0147588
Hauptverfasser:	Syed, Mansoor A, Choo-Wing, Rayman, Homer, Robert J, Bhandari, Vineet
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxydeoxyguanosine Alveoli Analysis Angiogenesis Animals Animals, Newborn - growth & development Biology and Life Sciences Blood Vessels - growth & development Blood Vessels - metabolism Cadherin Cadherins Cell adhesion & migration Cell growth Cell proliferation Collagen Doxycycline Drinking water Epithelial cells Female Genetic aspects Growth Hyperoxia Inhibition Injuries Isoforms Lung - growth & development Lung - metabolism Lung Injury - etiology Lung Injury - metabolism Lungs Male Markers Medicine Medicine and Health Sciences Mice Mice, Knockout Morphometry Neonates Newborn babies Newborn infants Nitric oxide Nitric Oxide Synthase - metabolism Nitric Oxide Synthase - physiology Nitric Oxide Synthase Type I - metabolism Nitric Oxide Synthase Type I - physiology Nitric Oxide Synthase Type II - metabolism Nitric Oxide Synthase Type II - physiology Nitric-oxide synthase Nitrotyrosine Oxidative stress Pathways Pediatrics Permeability Physical Sciences Physiological aspects Physiology Protein Isoforms - metabolism Proteins Pulmonary arteries Pulmonary hypertension Regulators Research and Analysis Methods Rodents Signaling Surfactants Transgenic Vascular endothelial growth factor Vascular Endothelial Growth Factor A - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!