Titanium Surface Priming with Phase-Transited Lysozyme to Establish a Silver Nanoparticle-Loaded Chitosan/Hyaluronic Acid Antibacterial Multilayer via Layer-by-Layer Self-Assembly

The formation of biofilm around implants, which is induced by immediate bacterial colonization after installation, is the primary cause of post-operation infection. Initial surface modification is usually required to incorporate antibacterial agents on titanium (Ti) surfaces to inhibit biofilm forma...

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Veröffentlicht in:	PloS one 2016-01, Vol.11 (1), p.e0146957
Hauptverfasser:	Zhong, Xue, Song, Yunjia, Yang, Peng, Wang, Yao, Jiang, Shaoyun, Zhang, Xu, Li, Changyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics Antiinfectives and antibacterials Antimicrobial agents Bacteria Biocompatibility Biofilms Biofilms - drug effects Biology and Life Sciences Biomedical materials Cell Line Cell Survival - drug effects Chemistry Chitosan Chitosan - chemistry Coated Materials, Biocompatible - pharmacology Coatings Colonization Controlled release Cytotoxicity Dental Implants - microbiology Dentistry Engineering and Technology Health aspects Hyaluronic acid Hyaluronic Acid - chemistry Hydroxyapatite Infections Lysozyme Materials science Medicine and Health Sciences Metal Nanoparticles - chemistry Mice Mucosa Nanoparticles Nosocomial infections Phosphine Physical Sciences Physiological aspects Priming Properties Protective coatings Research and Analysis Methods Self assembly Silver Silver - chemistry Substrates Surface Properties Surgical implants Sustained release Titanium Titanium - chemistry Titanium alloys Toxicity Transplants & implants X ray photoelectron spectroscopy
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