Glucose Alters Per2 Rhythmicity Independent of AMPK, Whereas AMPK Inhibitor Compound C Causes Profound Repression of Clock Genes and AgRP in mHypoE-37 Hypothalamic Neurons

Specific neurons in the hypothalamus are regulated by peripheral hormones and nutrients to maintain proper metabolic control. It is unclear if nutrients can directly control clock gene expression. We have therefore utilized the immortalized, hypothalamic cell line mHypoE-37, which exhibits robust ci...

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Veröffentlicht in:PloS one 2016-01, Vol.11 (1), p.e0146969
Hauptverfasser: Oosterman, Johanneke E, Belsham, Denise D
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Sprache:eng
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