Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents

Adolescence is a developmental period characterized by heightened vulnerability to illicit drug use and the onset of neuropsychiatric disorders. These clinical phenomena likely share common neurobiological substrates, as mesocorticolimbic dopamine systems actively mature during this period. Whereas...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2016-01, Vol.11 (1), p.e0146966
Hauptverfasser:	Dwyer, Jennifer B, Leslie, Frances M
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adolescence Adolescents Adults Age Age differences Aging - physiology Animals Behavior Binding sites Brain - metabolism Child development Circuits Cocaine Cortex Cytoskeletal Proteins - genetics Data processing Developmental stages Dopamine Dopamine Agonists - administration & dosage Dopamine Agonists - pharmacology Dopamine D1 receptors Dopamine D2 receptors Dopamine receptors Drug abuse Drug dosages Drugs Experiments Exploratory behavior Forebrain Gene expression Genetic aspects Hippocampus Humans Hypotheses Immediate-early proteins Male Maturation Mental disorders Metabolism Motor Activity - drug effects Motor Activity - physiology Nerve Tissue Proteins - genetics Network analysis Neural networks Pharmacology Physiological aspects Proteins Proto-Oncogene Proteins c-fos - genetics Psychological aspects Psychopathology Psychopharmacology Rats Rats, Sprague-Dawley Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - metabolism Recruitment Regional analysis Regional development Rodents Stereotyped Behavior - drug effects Stereotyped Behavior - physiology Stria terminalis Studies Substrates Teenagers Trajectory analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!